A variety of acute brain insults can induce epileptogenesis, a complex process that results in
acquired epilepsy. Despite advances in understanding mechanisms of epileptogenesis …

Traumatic brain injury (TBI) remains a significant leading cause of death and disability
among adults and children globally. To date, there are no Food and Drug Administration …

Levetiracetam (LEV) is an antiepileptic agent targeting novel pathways. Coupled with a
favorable safety profile and increasing empirical clinical use, it was the fifth drug tested by …

Traumatic brain injury (TBI), defined as a traumatic blow or jolt to the head, or penetrating
trauma to the skull that injures the brain, is a worldwide epidemic that has a substantial …

Excitotoxicity contributes to epileptogenesis after severe traumatic brain injury (sTBI).
Demographic and clinical risk factors for post-traumatic seizures (PTS) have been identified …

The aim of this review is to discuss the research presented in a symposium entitled “Current
progress in characterizing therapeutic strategies and challenges in experimental CNS …

Abstract Levetiracetam (LEV), a second-generation antiepileptic drug, is commonly
prescribed to treat certain types of seizures. Few studies have investigated the effects of LEV …

Pharmacotherapy for traumatic brain injury (TBI) is focused on resuscitation, prevention of
secondary injury, rehabilitation and recovery. Pharmacogenomics may play a role in TBI for …

The effects of traumatic brain injury (TBI) are heterogeneous and have limited predictability,
particularly in relation to neurorehabilitation. To address and treat the diverse sequelae that …

Effects of Different Doses of Levetiracetam on Aquaporin 4 Expression in Rats with Brain
Edema Following Fluid Percussion Injury - PMC Back to Top Skip to main content NIH NLM …