[HTML][HTML] Animal models of Alzheimer's disease: Applications, evaluation, and perspectives
ZY Chen, Y Zhang - Zoological Research, 2022 - ncbi.nlm.nih.gov
Although great advances in elucidating the molecular basis and pathogenesis of
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …
Alzheimer's disease (AD) have been made and multifarious novel therapeutic approaches …
Rodent models of neuroinflammation for Alzheimer's disease
A Nazem, R Sankowski, M Bacher… - Journal of …, 2015 - Springer
Alzheimer's disease remains incurable, and the failures of current disease-modifying
strategies for Alzheimer's disease could be attributed to a lack of in vivo models that …
strategies for Alzheimer's disease could be attributed to a lack of in vivo models that …
Okadaic acid: more than a diarrheic toxin
Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is
easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be …
easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be …
Zebrafish as a model organism for neurodegenerative disease
K Chia, A Klingseisen, D Sieger… - Frontiers in molecular …, 2022 - frontiersin.org
The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …
AlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research
H Liu, L Wang, M Lv, R Pei, P Li, Z Pei… - Journal of chemical …, 2014 - ACS Publications
Alzheimer's disease (AD) is one of the most complicated progressive neurodegeneration
diseases that involve many genes, proteins, and their complex interactions. No effective …
diseases that involve many genes, proteins, and their complex interactions. No effective …
Gold nanoparticles treatment reverses brain damage in Alzheimer's disease model
N dos Santos Tramontin, S da Silva, R Arruda… - Molecular …, 2020 - Springer
Alzheimer's disease (AD) is characterized by amyloid (A) β peptide accumulation and
intracellular neurofibrillary tangles. New hypotheses have suggested that AD involves …
intracellular neurofibrillary tangles. New hypotheses have suggested that AD involves …
Streptozotocin induced Alzheimer's disease like changes and the underlying neural degeneration and regeneration mechanism
PK Kamat - Neural regeneration research, 2015 - journals.lww.com
Alzheimer's disease (AD) is a neurodegenerative disorder which is remarkably
characterized by pathological hallmarks that include neurofibrillary tangles, neuronal loss …
characterized by pathological hallmarks that include neurofibrillary tangles, neuronal loss …
Okadaic acid induced neurotoxicity: an emerging tool to study Alzheimer's disease pathology
Okadaic acid (OKA) is one of the main polyether toxins produced by marine microalgae
which causes diarrhetic shellfish poisoning. It is a selective and potent inhibitor of …
which causes diarrhetic shellfish poisoning. It is a selective and potent inhibitor of …
Streptozotocin intracerebroventricular-induced neurotoxicity and brain insulin resistance: a therapeutic intervention for treatment of sporadic Alzheimer's disease (sAD …
Alzheimer's disease (AD) is a neurodegenerative disorder that is remarkably characterized
by pathological hallmarks which include amyloid plaques, neurofibrillary tangles, neuronal …
by pathological hallmarks which include amyloid plaques, neurofibrillary tangles, neuronal …
Toxin-induced experimental models of learning and memory impairment
Animal models for learning and memory have significantly contributed to novel strategies for
drug development and hence are an imperative part in the assessment of therapeutics …
drug development and hence are an imperative part in the assessment of therapeutics …