Indoleamine 2, 3-Dioxygenase (IDO) Activity: A Perspective Biomarker for Laboratory Determination in Tumor Immunotherapy

P Yang, J Zhang - Biomedicines, 2023 - mdpi.com
Indoleamine 2, 3-dioxygenase 1 (IDO1) is a heme enzyme involved in catalyzing the
conversion of tryptophan (Trp) into kynurenine (Kyn) at the first rate-limiting step in the …

Kynurenine Pathway in Psoriasis—a Promising Link?

A Stepaniuk, A Baran, I Flisiak - Dermatology and Therapy, 2023 - Springer
Psoriasis is a common dermatosis which affects the patient's skin and general well-being
because of its link to diseases such as depression, kidney disease and metabolic syndrome …

Alteration in kynurenine pathway metabolites in young women with autoimmune thyroiditis

A Krupa, A Łebkowska, M Kondraciuk, KA Kaminski… - Scientific Reports, 2024 - nature.com
The kynurenine pathway (KP) of tryptophan degradation includes several compounds that
reveal immunomodulatory properties. The present study aimed to investigate the alteration …

Effects of Fenofibrate and Gemfibrozil on Kynurenic Acid Production in Rat Kidneys In Vitro: Old Drugs, New Properties

I Zakrocka, T Kocki, E Urbańska, W Załuska - Life, 2023 - mdpi.com
Kidney dysfunction significantly increases the cardiovascular risk, even in cases of minor
functional declines. Hypertriglyceridemia is the most common lipid abnormality reported in …

Effect of fenofibrate and gemfibrozil on kynurenic acid production in rat kidney in vitro: old drugs, new possibilities

I Zakrocka, W Załuska - 2023 - researchsquare.com
Kidney dysfunction significantly increases cardiovascular risk, even in the setting of minor
function decline. Hypertriglyceridemia is the most common finding among lipid abnormalities …