The bacterial cell wall: from lipid II flipping to polymerization
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
Cell-wall recycling of the gram-negative bacteria and the nexus to antibiotic resistance
DA Dik, JF Fisher, S Mobashery - Chemical reviews, 2018 - ACS Publications
The importance of the cell wall to the viability of the bacterium is underscored by the breadth
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …
of antibiotic structures that act by blocking key enzymes that are tasked with cell-wall …
Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL
L Käshammer, F van den Ent, M Jeffery, NL Jean… - Nature …, 2023 - nature.com
In most bacteria, cell division relies on the synthesis of new cell wall material by the
multiprotein divisome complex. Thus, at the core of the divisome are the transglycosylase …
multiprotein divisome complex. Thus, at the core of the divisome are the transglycosylase …
Eco-friendly graphene oxide-based magnesium oxide nanocomposite synthesis using fungal fermented by-products and gamma rays for outstanding antimicrobial …
RM Fathy, AY Mahfouz - Journal of Nanostructure in Chemistry, 2021 - Springer
Green synthesis of nanoparticles is an eco-friendly new approach and an attractive field in
biomedical applications. In the current investigation, a novel green synthesis of magnesium …
biomedical applications. In the current investigation, a novel green synthesis of magnesium …
β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium
JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
Antibiotic action and resistance: updated review of mechanisms, spread, influencing factors, and alternative approaches for combating resistance
EM Halawa, M Fadel, MW Al-Rabia… - Frontiers in …, 2024 - frontiersin.org
Antibiotics represent a frequently employed therapeutic modality for the management of
bacterial infections across diverse domains, including human health, agriculture, livestock …
bacterial infections across diverse domains, including human health, agriculture, livestock …
Penicillin binding protein 2a: An overview and a medicinal chemistry perspective
MAW Shalaby, EME Dokla, RAT Serya… - European Journal of …, 2020 - Elsevier
Antimicrobial resistance is an imminent threat worldwide. Methicillin-resistant
Staphylococcus aureus (MRSA) is one of the “superbug” family, manifesting resistance …
Staphylococcus aureus (MRSA) is one of the “superbug” family, manifesting resistance …
Nucleotide sugars in chemistry and biology
S Mikkola - Molecules, 2020 - mdpi.com
Nucleotide sugars have essential roles in every living creature. They are the building blocks
of the biosynthesis of carbohydrates and their conjugates. They are involved in processes …
of the biosynthesis of carbohydrates and their conjugates. They are involved in processes …
Novel opportunity to reverse antibiotic resistance: to explore traditional Chinese medicine with potential activity against antibiotics-resistance bacteria
T Su, Y Qiu, X Hua, B Ye, H Luo, D Liu, P Qu… - Frontiers in …, 2020 - frontiersin.org
Antibiotic resistance is becoming significantly prominent and urgent in clinical practice with
the increasing and wide application of antibacterial drugs. However, developing and …
the increasing and wide application of antibacterial drugs. However, developing and …
Multimodal role of amino acids in microbial control and drug development
M Idrees, AR Mohammad, N Karodia, A Rahman - Antibiotics, 2020 - mdpi.com
Amino acids are ubiquitous vital biomolecules found in all kinds of living organisms
including those in the microbial world. They are utilised as nutrients and control many …
including those in the microbial world. They are utilised as nutrients and control many …