Study of interaction between different solvents and neurotransmitters dopamine, l-adrenaline, and l-noradrenaline using LED, QTAIM and AIMD

R Thomas, T Pooventhiran, MA Bakht… - Journal of Molecular …, 2022 - Elsevier
In this research article, we report the computational solvation studies of three
neurotransmitters dopamine, l-adrenaline, and l-noradrenaline are generally active …

Chiral MoSe2 Nanoparticles for Ultrasensitive Monitoring of Reactive Oxygen Species In Vivo

B Cao, H Zhang, M Sun, C Xu, H Kuang… - Advanced …, 2024 - Wiley Online Library
Reactive oxygen species (ROS) are involved in neurodegenerative diseases, cancer, and
acute hepatitis, and quantification of ROS is critical for the early diagnosis of these diseases …

Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila

M Majcin Dorcikova, LC Duret, E Pottié… - Nature …, 2023 - nature.com
Sleep and circadian rhythm disruptions are frequent comorbidities of Parkinson's disease
(PD), a disorder characterized by the progressive loss of dopaminergic (DA) neurons in the …

An adult-stage transcriptional program for survival of serotonergic connectivity

MM Kitt, N Tabuchi, WC Spencer, HL Robinson… - Cell reports, 2022 - cell.com
Neurons must function for decades of life, but how these non-dividing cells are preserved is
poorly understood. Using mouse serotonin (5-HT) neurons as a model, we report an adult …

[HTML][HTML] Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation

S Hembach, S Schmidt, T Orschmann, I Burtscher… - Neurobiology of …, 2024 - Elsevier
A key pathological feature of Parkinson's Disease (PD) is the progressive degeneration of
dopaminergic neurons (DAns) in the substantia nigra pars compacta. Considering the major …

Lysosomal TFEB‐TRPML1 Axis in Astrocytes Modulates Depressive‐like Behaviors

JW Mo, PL Kong, L Ding, J Fan, J Ren, CL Lu… - Advanced …, 2024 - Wiley Online Library
Lysosomes are important cellular structures for human health as centers for recycling,
signaling, metabolism and stress adaptation. However, the potential role of lysosomes in …

Structural insights into the recognition of the A/T‐rich motif in target gene promoters by the LMX 1a homeobox domain

L Lin, J Deng, J Peng, J Cui, L Wang… - The FEBS …, 2024 - Wiley Online Library
LIM homeodomain transcription factor 1‐alpha (LMX1a) is a neuronal lineage‐specific
transcription activator that plays an essential role during the development of midbrain …

The utility and caveat of split-GAL4s in the study of neurodegeneration

L Stickley, R Koch, E Nagoshi - Fly, 2023 - Taylor & Francis
Parkinson's disease (PD) is the second most common neurodegenerative disorder, afflicting
over 1% of the population of age 60 y and above. The loss of dopaminergic (DA) neurons in …

The lncRNA lnc_AABR07044470. 1 promotes the mitochondrial-damaged inflammatory response to neuronal injury via miR-214-3p/PERM1 axis in acute ischemic …

M Wang, H Li, Y Qian, S Zhao, H Wang, Y Wang… - Molecular Biology …, 2024 - Springer
Purpose We investigated the role of lnc_AABR07044470. 1 on the occurrence and
development of acute ischemic stroke (AIS) and neuronal injury by targeting the miR-214 …

Prediction Algorithm of DNA Sites Based on Weighted Feature Matrix

Z Liu, X Chen, D Li, X Lv, D Zhu… - 2022 IEEE International …, 2022 - ieeexplore.ieee.org
DNA sites can realize various biological functions and play an important role in many
biological activities. However, due to the complexity of feature extraction, feature learning is …