Microneedle-mediated transdermal delivery of biopharmaceuticals
HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …
administration. However, this strategy is generally limited to a few molecules with specific …
Progress in microneedle-mediated protein delivery
The growing demand for patient-compliance therapies in recent years has led to the
development of transdermal drug delivery, which possesses several advantages compared …
development of transdermal drug delivery, which possesses several advantages compared …
Electroanalytical sensor based on gold-nanoparticle-decorated paper for sensitive detection of copper ions in sweat and serum
The growth of (bio) sensors in analytical chemistry is mainly attributable to the development
of affordable, effective, portable, and user-friendly analytical tools. In the field of sensors …
of affordable, effective, portable, and user-friendly analytical tools. In the field of sensors …
A comprehensive analysis of the intrinsic visible fluorescence emitted by peptide/protein amyloid-like assemblies
Amyloid aggregation is a widespread process that involves proteins and peptides with
different molecular complexity and amino acid composition. The structural motif (cross-β) …
different molecular complexity and amino acid composition. The structural motif (cross-β) …
A Diruthenium Metallodrug as a Potent Inhibitor of Amyloid-β Aggregation: Synergism of Mechanisms of Action
S La Manna, C Di Natale, V Panzetta, M Leone… - Inorganic …, 2023 - ACS Publications
The physical and chemical properties of paddlewheel diruthenium compounds are highly
dependent on the nature of the ligands surrounding the bimetallic core. Herein, we compare …
dependent on the nature of the ligands surrounding the bimetallic core. Herein, we compare …
Glucosyl platinum (II) complexes inhibit aggregation of the C-terminal region of the Aβ peptide
S La Manna, M Leone, I Iacobucci… - Inorganic …, 2022 - ACS Publications
Neurodegenerative diseases are often caused by uncontrolled amyloid aggregation. Hence,
many drug discovery processes are oriented to evaluate new compounds that are able to …
many drug discovery processes are oriented to evaluate new compounds that are able to …
Plant isoquinoline alkaloids as potential neurodrugs: A comparative study of the effects of benzo [c] phenanthridine and berberine-based compounds on β-amyloid …
Herein we present a comparative study of the effects of isoquinoline alkaloids belonging to
benzo [c] phenanthridine and berberine families on β-amyloid aggregation. Results …
benzo [c] phenanthridine and berberine families on β-amyloid aggregation. Results …
A comparative study of the effects of platinum (II) complexes on β-amyloid aggregation: Potential neurodrug applications
SL Manna, D Florio, I Iacobucci, F Napolitano… - International journal of …, 2021 - mdpi.com
Herein the effects of three platinum complexes, namely (SP-4-2)-(2, 2′-bipyridine)
dichloridoplatinum (II), Pt-bpy,(SP-4-2)-dichlorido (1, 10-phenanthroline) platinum (II), Pt …
dichloridoplatinum (II), Pt-bpy,(SP-4-2)-dichlorido (1, 10-phenanthroline) platinum (II), Pt …
PLGA microparticle formulations for tunable delivery of a nano-engineered filamentous bacteriophage-based vaccine: in vitro and in silico-supported approach
Bacteriophages have attracted great attention in the bioengineering field in diverse research
areas from tissue engineering to therapeutic and clinical applications. Recombinant …
areas from tissue engineering to therapeutic and clinical applications. Recombinant …
Metal–peptide complexes as promising antibiotics to fight emerging drug resistance: New perspectives in tuberculosis
C Di Natale, I De Benedictis, A De Benedictis… - Antibiotics, 2020 - mdpi.com
In metal-peptide interactions, cations form stable complexes through bonds with
coordinating groups as side chains of amino acids. These compounds, among other things …
coordinating groups as side chains of amino acids. These compounds, among other things …