The liver cancer immune microenvironment: Therapeutic implications for hepatocellular carcinoma
R Donne, A Lujambio - Hepatology, 2023 - journals.lww.com
The liver is the sixth most common site of primary cancer in humans and the fourth leading
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
cause of cancer‐related death in the world. Hepatocellular carcinoma (HCC) accounts for …
Global epidemiology and genetics of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is one of the leading cancers worldwide. Classically, HCC
develops in genetically susceptible individuals who are exposed to risk factors, especially in …
develops in genetically susceptible individuals who are exposed to risk factors, especially in …
Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)
X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - Signal transduction and …, 2022 - nature.com
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
KM Schneider, A Mohs, W Gui, EJC Galvez… - Nature …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide,
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …
Gut–liver axis: barriers and functional circuits
The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …
microbiome, diet and other environmental factors. The sum of these interactions is …
[HTML][HTML] Gut microbiome is associated with the clinical response to anti-PD-1 based immunotherapy in hepatobiliary cancers
Background The gut microbiome is associated with the response to immunotherapy for
different cancers. However, the impact of the gut microbiome on hepatobiliary cancers …
different cancers. However, the impact of the gut microbiome on hepatobiliary cancers …
NAFLD-driven HCC: Safety and efficacy of current and emerging treatment options
In light of a global rise in obesity and type 2 diabetes, non-alcoholic fatty liver disease
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
(NAFLD) and non-alcoholic steatohepatitis (NASH) represent an increasingly important …
Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy
Oncogenesis is associated with intestinal dysbiosis, and stool shotgun metagenomic
sequencing in individuals with this condition might constitute a non-invasive approach for …
sequencing in individuals with this condition might constitute a non-invasive approach for …
[HTML][HTML] Multi-'omics of gut microbiome-host interactions in short-and long-term myalgic encephalomyelitis/chronic fatigue syndrome patients
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, debilitating
disorder manifesting as severe fatigue and post-exertional malaise. The etiology of ME/CFS …
disorder manifesting as severe fatigue and post-exertional malaise. The etiology of ME/CFS …
Gut microbiota participates in polystyrene microplastics-induced hepatic injuries by modulating the gut–liver axis
K Zhang, J Yang, L Chen, J He, D Qu, Z Zhang, Y Liu… - ACS …, 2023 - ACS Publications
Dietary pollution by polystyrene microplastics (MPs) can cause hepatic injuries and
microbial dysbiosis. Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea …
microbial dysbiosis. Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea …