Inspired by natural biology, cell membrane-mimetic surface engineering and cell membrane
camouflaging technology have been widely investigated. Notably, the cell membrane …

The incidence of colorectal cancer (CRC) is on the rise, and the prognosis for patients with
recurrent or metastatic disease is extremely poor. Although chemotherapy and radiation …

Despite multiple immunotherapeutic technologies that achieve potent T cell activation,
effector T cells still lack efficiency because of the highly immunosuppressive conditions in …

Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using
exogenous antigens and adoptive cells, we show a concept of utilizing biologically …

Using the cytomembranes (FMs) of hybrid cells acquired from the fusion of cancer and
dendritic cells (DCs), this study offers a biologically derived platform for the combination of …

It is now possible to grow DC-like cells in culture17-21 and extensive cell membrane
processes that are acquired late the first monoclonal antibodies (MoAbs) 22, 23 that react …

Metastasis is the leading cause of cancer‐associated death, with poor prognosis even after
extensive treatment. The dormancy of metastatic cancer cells during dissemination or after …

MUC1 is a large, heavily glycosylated mucin expressed on the apical surfaces of most
simple, secretory epithelia including the mammary gland, gastrointestinal, respiratory …

The development of cancer is a multi-step process involving the gradual loss of regulation
over the growth and functional capabilities of normal cells. Much research has been focused …

Abstract Purpose: Dendritic cells (DCs) are potent antigen-presenting cells that are uniquely
capable of inducing tumor-specific immune responses. We have conducted a Phase I trial in …