Cannabinoids and the gut: new developments and emerging concepts

AA Izzo, KA Sharkey - Pharmacology & therapeutics, 2010 - Elsevier
Cannabis has been used to treat gastrointestinal (GI) conditions that range from enteric
infections and inflammatory conditions to disorders of motility, emesis and abdominal pain …

[HTML][HTML] G-protein-coupled receptors in intestinal chemosensation

F Reimann, G Tolhurst, FM Gribble - Cell metabolism, 2012 - cell.com
Food intake is detected by the chemical senses of taste and smell and subsequently by
chemosensory cells in the gastrointestinal tract that link the composition of ingested foods to …

A cannabinoid link between mitochondria and memory

E Hebert-Chatelain, T Desprez, R Serrat, L Bellocchio… - Nature, 2016 - nature.com
Cellular activity in the brain depends on the high energetic support provided by
mitochondria, the cell organelles which use energy sources to generate ATP,,,. Acute …

Endocannabinoids in the Gut

NV DiPatrizio - Cannabis and cannabinoid research, 2016 - liebertpub.com
Cannabis has been used medicinally for centuries to treat a variety of disorders, including
those associated with the gastrointestinal tract. The discovery of our bodies' own “cannabis …

Targeting the endocannabinoid system for the treatment of abdominal pain in irritable bowel syndrome

SM Brierley, B Greenwood-Van Meerveld… - Nature Reviews …, 2023 - nature.com
The management of visceral pain in patients with disorders of gut–brain interaction, notably
irritable bowel syndrome, presents a considerable clinical challenge, with few available …

The gastrointestinal tract–a central organ of cannabinoid signaling in health and disease

C Hasenoehrl, U Taschler, M Storr… - Neurogastroenterology …, 2016 - Wiley Online Library
Background In ancient medicine, extracts of the marijuana plant Cannabis sativa were used
against diseases of the gastrointestinal (GI) tract. Today, our knowledge of the ingredients of …

[HTML][HTML] Effect of high fat-diet and obesity on gastrointestinal motility

M Al Mushref, S Srinivasan - Annals of translational medicine, 2013 - ncbi.nlm.nih.gov
Obesity is highly prevalent worldwide and is associated with significant morbidity and
mortality. The focus of this review is to delineate the changes in gastrointestinal motility …

[HTML][HTML] Cannabinoids and opioids in the treatment of inflammatory bowel diseases

M Kienzl, M Storr, R Schicho - Clinical and translational …, 2020 - journals.lww.com
In traditional medicine, Cannabis sativa has been prescribed for a variety of diseases.
Today, the plant is largely known for its recreational purpose, but it may find a way back to …

Mitochondrial calcium at the synapse

S Datta, M Jaiswal - Mitochondrion, 2021 - Elsevier
Mitochondria are dynamic organelles, which serve various purposes, including but not
limited to the production of ATP and various metabolites, buffering ions, acting as a signaling …

Mitochondria as central hubs in synaptic modulation

FV Duarte, D Ciampi, CB Duarte - Cellular and Molecular Life Sciences, 2023 - Springer
Mitochondria are present in the pre-and post-synaptic regions, providing the energy
required for the activity of these very specialized neuronal compartments. Biogenesis of …