[HTML][HTML] Current advances in protein import into peroxisomes

T Walter, R Erdmann - The Protein Journal, 2019 - Springer
Blobel and coworkers discovered in 1978 that peroxisomal proteins are synthesized on free
ribosomes in the cytosol and thus provided the grounds for the conception of peroxisomes …

[HTML][HTML] The type-2 peroxisomal targeting signal

M Kunze - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
The type-2 peroxisomal targeting signal (PTS2) is one of two peptide motifs destining
soluble proteins for peroxisomes. This signal acts as amphiphilic α-helix exposing the side …

A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast

S Gabay-Maskit, LD Cruz-Zaragoza… - Journal of cell …, 2020 - journals.biologists.com
Eukaryotic cells have evolved organelles that allow the compartmentalization and regulation
of metabolic processes. Knowledge of molecular mechanisms that allow temporal and …

Two NAD-linked redox shuttles maintain the peroxisomal redox balance in Saccharomyces cerevisiae

NA Al-Saryi, MY Al-Hejjaj, CWT van Roermund… - Scientific reports, 2017 - nature.com
In Saccharomyces cerevisiae, peroxisomes are the sole site of fatty acid β-oxidation. During
this process, NAD+ is reduced to NADH. When cells are grown on oleate medium …

Good things come to those who bait: the peroxisomal docking complex

M Rüttermann, C Gatsogiannis - Biological chemistry, 2023 - degruyter.com
Peroxisomal integrity and function are highly dependent on its membrane and soluble
(matrix) components. Matrix enzymes are imported post-translationally in a folded or even …

Long chain acyl CoA synthetase 4 catalyzes the first step in peroxisomal indole-3-butyric acid to IAA conversion

V Jawahir, BK Zolman - Plant Physiology, 2021 - academic.oup.com
Abstract Indole-3-butyric acid (IBA) is an endogenous storage auxin important for
maintaining appropriate indole-3-acetic acid (IAA) levels, thereby influencingprimary root …

Defining the mammalian peroxisomal proteome

E Yifrach, S Fischer, S Oeljeklaus, M Schuldiner… - … Novel Functions and …, 2018 - Springer
The current view on peroxisomes has changed dramatically from being human cell oddities
to vital organelles that host several key metabolic pathways. To fulfil over 50 different …

The budding yeast Pex5p receptor directs Fox2p and Cta1p into peroxisomes via its N-terminal region near the FxxxW domain

Ł Rymer, B Kempiński, A Chełstowska… - Journal of Cell …, 2018 - journals.biologists.com
The import of most of peroxisomal proteins into the lumen of their target organelle is driven
by C-terminal (PTS1) or N-terminal (PTS2) signals recognized by the Pex5p or Pex7p …

Analysis of potential redundancy among Arabidopsis 6-phosphogluconolactonase isoforms in peroxisomes

H Lansing, L Doering, K Fischer… - Journal of …, 2020 - academic.oup.com
Recent work revealed that PGD2, an Arabidopsis 6-phosphogluconate dehydrogenase (6-
PGD) catalysing the third step of the oxidative pentose-phosphate pathway (OPPP) in …

Genomic and Proteomic Evidence for the Presence of a Peroxisome in the Apicomplexan Parasite Toxoplasma gondii and Other Coccidia

D Moog, JM Przyborski, UG Maier - Genome biology and …, 2017 - academic.oup.com
Apicomplexans are successful parasites responsible for severe human diseases including
malaria, toxoplasmosis, and cryptosporidiosis. For many years, it has been discussed …