Background Moderate correlation exists between the imaging quantification of brain white
matter lesions and cognitive performance in people with multiple sclerosis (MS). This may …

Abstract Although Alois Alzheimer described myelin disruption in Alzheimer's disease (AD)
as early as in 1911, his observation has escaped the attention of researchers since that time …

Objective: To investigate whether extent and severity of white matter (WM) damage, as
measured with diffusion tensor imaging (DTI), can distinguish cognitively preserved (CP) …

It is increasingly recognized that cognitive symptoms are a common sequelae of relapsing-
remitting multiple sclerosis and are associated with adverse functional consequences …

Diffusion tensor imaging (DTI) is a sensitive tool for detecting microstructural tissue damage
in vivo. In this study, we investigated DTI abnormalities in individuals with relapsing remitting …

Background: While neuropsychological deficits have been reported in healthy individuals
who use street cannabis, data in patients with multiple sclerosis (MS) are lacking. Given that …

Although deep grey matter (GM) involvement in multiple sclerosis (MS) is well documented,
in-vivo multi-parameter magnetic resonance imaging (MRI) studies and association with …

More than 50% of multiple sclerosis patients develop cognitive impairment. However, the
underlying mechanisms are still unclear and there is no effective treatment. LINGO-1 (LRR …

Objectives: The objectives of this paper are to compare in a multicenter setting patterns of
regional cortical thickness in patients with relapsing–remitting multiple sclerosis (RRMS) …

BACKGROUND AND PURPOSE: The association between subcortical deep gray matter,
white matter, and cortical pathology is not well understood in MS. The aim of this study was …