Nanogels are three-dimensional nanoscale networks formed by physically or chemically
cross-linking polymers. Nanogels have been explored as drug delivery systems due to their …

Simple Summary Integrins, a superfamily of cell adhesion receptors, were extensively
investigated as therapeutic targets over the last decades, motivated by their multiple …

With the recent FDA approval of the first siRNA‐derived therapeutic, RNA interference
(RNAi)‐mediated gene therapy is undergoing a transition from research to the clinical …

Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major
issue for modern societies as a consequence of their progressive ageing. Even though …

Biological nanoparticles, such as exosomes, offer an approach to drug delivery because of
their innate ability to transport biomolecules. Exosomes are derived from cells and an …

Numerous nano drug delivery systems have been developed for preclinical cancer research
in the past 15 years with the hope for a fundamental change in oncology. The robust …

Biological systems have developed an efficient multi-tiered defense system to block foreign
substances such as engineered nanomaterials (NMs) from causing damage. In a …

Immunogenic cell death (ICD)‐induced immunotherapy holds promise for complete
elimination and long‐term protective immune responses against cancer by combining direct …

Photodynamic therapy (PDT) is a promising cancer treatment which involves a
photosensitizer (PS), light at a specific wavelength for PS activation and oxygen, which …