High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis
Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …
CFD for evaluation and treatment planning of aneurysms: review of proposed clinical uses and their challenges
B Chung, JR Cebral - Annals of biomedical engineering, 2015 - Springer
Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …
Distinctive flow pattern of wall shear stress and oscillatory shear index: similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs
T Kawaguchi, S Nishimura, M Kanamori… - Journal of …, 2012 - thejns.org
Object The difference in the hemodynamics of wall shear stress (WSS) and oscillatory shear
index (OSI) between ruptured and unruptured aneurysms is not well understood. The …
index (OSI) between ruptured and unruptured aneurysms is not well understood. The …
Hemodynamics and anatomy of elastase-induced rabbit aneurysm models: similarity to human cerebral aneurysms?
Z Zeng, DF Kallmes, MJ Durka, Y Ding… - American journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Animal models provide a mechanism for fundamental
studies of the coupling between hemodynamics and pathophysiology in diseases such as …
studies of the coupling between hemodynamics and pathophysiology in diseases such as …
Computational fluid dynamics of vascular disease in animal models
Recent applications of computational fluid dynamics (CFD) applied to the cardiovascular
system have demonstrated its power in investigating the impact of hemodynamics on …
system have demonstrated its power in investigating the impact of hemodynamics on …
From bench to bedside: utility of the rabbit elastase aneurysm model in preclinical studies of intracranial aneurysm treatment
W Brinjikji, YH Ding, DF Kallmes… - Journal of …, 2016 - jnis.bmj.com
Preclinical studies are important in helping practitioners and device developers improve
techniques and tools for endovascular treatment of intracranial aneurysms. Thus an …
techniques and tools for endovascular treatment of intracranial aneurysms. Thus an …
Genetic correlates of wall shear stress in a patient-specific 3D-printed cerebral aneurysm model
Objectives To study the correlation between wall shear stress and endothelial cell
expression in a patient-specific, three-dimensional (3D)-printed model of a cerebral …
expression in a patient-specific, three-dimensional (3D)-printed model of a cerebral …
[PDF][PDF] Influence of parent artery segmentation and boundary conditions on hemodynamic characteristics of intracranial aneurysms
Y Hua, JH Oh, YB Kim - Yonsei medical journal, 2015 - synapse.koreamed.org
Purpose The purpose of this study is to explore the influence of segmentation of the
upstream and downstream parent artery and hemodynamic boundary conditions (BCs) on …
upstream and downstream parent artery and hemodynamic boundary conditions (BCs) on …
Rabbit aneurysm models mimic histologic wall types identified in human intracranial aneurysms
S Wang, D Dai, PK Parameswaran… - Journal of …, 2018 - jnis.bmj.com
Background Semiquantitative scales correlate histopathologic findings in the walls of human
aneurysms with rupture status. Objective To apply a semiquantitative scale to the rabbit …
aneurysms with rupture status. Objective To apply a semiquantitative scale to the rabbit …
Cerebral aneurysm blood flow simulations are sensitive to basic solver settings
KD Dennis, DF Kallmes, D Dragomir-Daescu - Journal of biomechanics, 2017 - Elsevier
Computational modeling of peri-aneurysmal hemodynamics is typically carried out with
commercial software without knowledge of the sensitivity of the model to variation in input …
commercial software without knowledge of the sensitivity of the model to variation in input …