Increasing detection of unruptured intracranial aneurysms, catastrophic outcomes from
subarachnoid hemorrhage, and risks and cost of treatment necessitate defining objective …

Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …

Object The difference in the hemodynamics of wall shear stress (WSS) and oscillatory shear
index (OSI) between ruptured and unruptured aneurysms is not well understood. The …

BACKGROUND AND PURPOSE: Animal models provide a mechanism for fundamental
studies of the coupling between hemodynamics and pathophysiology in diseases such as …

Recent applications of computational fluid dynamics (CFD) applied to the cardiovascular
system have demonstrated its power in investigating the impact of hemodynamics on …

Preclinical studies are important in helping practitioners and device developers improve
techniques and tools for endovascular treatment of intracranial aneurysms. Thus an …

Objectives To study the correlation between wall shear stress and endothelial cell
expression in a patient-specific, three-dimensional (3D)-printed model of a cerebral …

Purpose The purpose of this study is to explore the influence of segmentation of the
upstream and downstream parent artery and hemodynamic boundary conditions (BCs) on …

Background Semiquantitative scales correlate histopathologic findings in the walls of human
aneurysms with rupture status. Objective To apply a semiquantitative scale to the rabbit …

Computational modeling of peri-aneurysmal hemodynamics is typically carried out with
commercial software without knowledge of the sensitivity of the model to variation in input …