Objective: To decide whether the use of blood lactate monitoring in critical care practice is
appropriate. We performed a systematic health technology assessment as blood lactate …

Critical illness is characterized by disruptions in homeostasis that result in single-or multiple-
organ injury and reversible or irreversible organ dysfunction. To a large extent, the duration …

Background Although therapeutic concepts of patients with major trauma have improved
during recent years, organ dysfunction still remains a frequent complication during clinical …

Postpartum hemorrhage: Blood product management and massive transfusion -
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BACKGROUND Often the clinician is faced with a diagnostic and therapeutic dilemma in
patients with concomitant traumatic brain injury (TBI) and hemorrhagic shock (HS), as rapid …

Despite the large number of endpoints available to the clinician, none are universally
applicable and none have independently demonstrated improved survival when guiding …

Hyperlactataemia is commonly used as a diagnostic and prognostic tool in intensive care
settings. Recent studies documented that serial lactate measurements over time (or lactate …

BACKGROUND: Early predictors of morbidity after cardiac operations are lacking. Elevated
lactate concentrations in the immediate postoperative period reflect unmet metabolic …

OBJECTIVES: The aims of the present study were to analyze patient-and management-
related predictors for outcome after open (OR) and endovascular repair (EVAR) of ruptured …

Background: Although blood lactate concentrations have an established prognostic value in
circulatory shock or after cardiac arrest, their relationship with morbidity and length of stay in …