Viral hepatocarcinogenesis
WL Tsai, RT Chung - Oncogene, 2010 - nature.com
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading
cause of cancer death worldwide. Despite recent advances in the diagnosis and treatment of …
cause of cancer death worldwide. Despite recent advances in the diagnosis and treatment of …
The role of chemokines in acute liver injury
Y Saiman, SL Friedman - Frontiers in physiology, 2012 - frontiersin.org
Chemokines are small molecular weight proteins primarily known to drive migration of
immune cell populations. In both acute and chronic liver injury, hepatic chemokine …
immune cell populations. In both acute and chronic liver injury, hepatic chemokine …
[PDF][PDF] Hepatitis C virus infection: molecular pathways to metabolic syndrome
MY Sheikh, J Choi, I Qadri, JE Friedman… - Hepatology, 2008 - Wiley Online Library
Chronic infection with hepatitis C virus (HCV) can induce insulin resistance (IR) in a
genotype‐dependent fashion, thus contributing to steatosis, progression of fibrosis and …
genotype‐dependent fashion, thus contributing to steatosis, progression of fibrosis and …
Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2
D Selimovic, M Hassan, Y Haikel, UR Hengge - Cellular Signalling, 2008 - Elsevier
Taxol (paclitaxel) is a new antineoplastic drug that has shown promise in the treatment of
different tumor types. However, the molecular mechanisms governing taxol-induced …
different tumor types. However, the molecular mechanisms governing taxol-induced …
[HTML][HTML] Hepatitis C virus and hepatocarcinogenesis
SW Jeong, JY Jang, RT Chung - Clinical and molecular …, 2012 - ncbi.nlm.nih.gov
Hepatitis C virus (HCV) is an RNA virus that is unable to integrate into the host genome.
However, its proteins interact with various host proteins and induce host responses. The …
However, its proteins interact with various host proteins and induce host responses. The …
[PDF][PDF] Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways
Chronic hepatitis C virus (HCV) infection is associated with the production of serum
cytokines, including transforming growth factor (TGF)‐β2. Despite the occurrence of hepatic …
cytokines, including transforming growth factor (TGF)‐β2. Despite the occurrence of hepatic …
Role of nuclear factor κB in liver health and disease
SM Robinson, DA Mann - Clinical science, 2010 - portlandpress.com
NF-κB (nuclear factor κB) is a heterodimeric transcription factor that is constitutively
expressed in all cell types and has a central role as a transcriptional regulator in response to …
expressed in all cell types and has a central role as a transcriptional regulator in response to …
The oral cavity of elderly patients in diabetes
Diabetes mellitus is a common and growing global health problem leading to several
complications. Among these periodontal diseases are considered as the sixth complication …
complications. Among these periodontal diseases are considered as the sixth complication …
Hepatitis C and diabetes: the inevitable coincidence?
Type 2 diabetes (T2D) and HCV infection are common conditions involving, respectively, at
least 170 and 130 million people worldwide. However, the distribution of such cases does …
least 170 and 130 million people worldwide. However, the distribution of such cases does …
[PDF][PDF] Hepatitis C virus infection enhances TNFα‐induced cell death via suppression of NF‐κB
Hepatitis C virus (HCV) infection results in liver injury and long‐term complications, such as
liver cirrhosis and hepatocellular carcinoma. Liver injury in HCV infection is believed to be …
liver cirrhosis and hepatocellular carcinoma. Liver injury in HCV infection is believed to be …