Matrix metalloproteinases, vascular remodeling, and vascular disease

X Wang, RA Khalil - Advances in pharmacology, 2018 - Elsevier
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that
degrade various proteins in the extracellular matrix (ECM). Typically, MMPs have a …

Matrix metalloproteinases as biomarkers of atherosclerotic plaque instability

W Olejarz, D Łacheta… - International journal of …, 2020 - mdpi.com
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases
responsible for tissue remodeling and degradation of extracellular matrix (ECM) proteins …

Matrix metalloproteinase-9: Many shades of function in cardiovascular disease

A Yabluchanskiy, Y Ma, RP Iyer, ME Hall… - …, 2013 - journals.physiology.org
Matrix metalloproteinase (MMP)-9, one of the most widely investigated MMPs, regulates
pathological remodeling processes that involve inflammation and fibrosis in cardiovascular …

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

S Kaptoge, SRK Seshasai, P Gao… - European heart …, 2014 - academic.oup.com
Aims Because low-grade inflammation may play a role in the pathogenesis of coronary heart
disease (CHD), and pro-inflammatory cytokines govern inflammatory cascades, this study …

Periodontal systemic associations: review of the evidence

GJ Linden, A Lyons… - Journal of periodontology, 2013 - Wiley Online Library
Aim: To critically appraise recent research into associations between periodontal disease
and systemic diseases and conditions specifically respiratory disease, chronic kidney …

The role of matrix metalloproteinase‐9 in atherosclerotic plaque instability

T Li, X Li, Y Feng, G Dong, Y Wang… - Mediators of …, 2020 - Wiley Online Library
Matrix metalloproteinase‐9 (MMP‐9) belongs to the MMP family and has been widely
investigated. Excessive MMP‐9 expression can enhance extracellular matrix degradation …

Matrix metalloproteinases in myocardial infarction and heart failure

KY DeLeon-Pennell, CA Meschiari, M Jung… - Progress in molecular …, 2017 - Elsevier
Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …

Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases

T Sorsa, UK Gursoy, S Nwhator… - Periodontology …, 2016 - Wiley Online Library
Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

Metalloproteinases in atherosclerosis

JL Johnson - European journal of pharmacology, 2017 - Elsevier
Atherosclerosis underlies most cardiovascular diseases, and is accepted as a primary cause
of mortality worldwide. Proteases have been implicated in the development and progression …

Biomarkers of cardiovascular disease: molecular basis and practical considerations

RS Vasan - Circulation, 2006 - Am Heart Assoc
echocardiogram) may be expected to facilitate the identification of patients with chest pain of
an ischemic etiology (angina). In a patient presenting to the emergency department with …