Nucleic acid tests for clinical translation
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
natural biopolymers composed of nucleotides that store, transmit, and express genetic …
Electrochemical methods for the analysis of clinically relevant biomolecules
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …
demand for high-performance detection technologies. Implementation of electrochemical …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
Aptasensor with expanded nucleotide using DNA nanotetrahedra for electrochemical detection of cancerous exosomes
Exosomes are extracellular vesicles (50–100 nm) circulating in biofluids as intercellular
signal transmitters. Although the potential of cancerous exosomes as tumor biomarkers is …
signal transmitters. Although the potential of cancerous exosomes as tumor biomarkers is …
[HTML][HTML] From cascaded catalytic nucleic acids to enzyme–DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures
DNA is one of the most fascinating biopolymers. Besides its central role as carrier of genetic
information and translation of the genetic code into proteins, DNA holds great promise as a …
information and translation of the genetic code into proteins, DNA holds great promise as a …
Triplex DNA nanostructures: from basic properties to applications
Triplex nucleic acids have recently attracted interest as part of the rich “toolbox” of structures
used to develop DNA‐based nanostructures and materials. This Review addresses the use …
used to develop DNA‐based nanostructures and materials. This Review addresses the use …
Hybridization chain reaction amplification of microRNA detection with a tetrahedral DNA nanostructure-based electrochemical biosensor
There remains a great challenge in the sensitive detection of microRNA because of the short
length and low abundance of microRNAs in cells. Here, we have demonstrated an …
length and low abundance of microRNAs in cells. Here, we have demonstrated an …
Gold nanoparticle aggregation-induced quantitative photothermal biosensing using a thermometer: a simple and universal biosensing platform
A simple, low-cost, and universal gold nanoparticle (AuNP) aggregation-induced
photothermal biosensing platform has been developed for the first time and applied for the …
photothermal biosensing platform has been developed for the first time and applied for the …
The recent development of hybridization chain reaction strategies in biosensors
C Zhang, J Chen, R Sun, Z Huang, Z Luo, C Zhou… - ACS …, 2020 - ACS Publications
With the continuous development of biosensors, researchers have focused increasing
attention on various signal amplification strategies to pursue superior performance for more …
attention on various signal amplification strategies to pursue superior performance for more …
Recent development of sandwich assay based on the nanobiotechnologies for proteins, nucleic acids, small molecules, and ions
For decades, the sandwich assay has been a mainstay in the fields of biodetection, clinical
diagnostics, environmental monitoring, and quality control in various industries. By …
diagnostics, environmental monitoring, and quality control in various industries. By …