Low programmed death-ligand 1–expressing subgroup outcomes of first-line immune checkpoint inhibitors in gastric or esophageal adenocarcinoma
PURPOSE The US Food and Drug Administration has granted regulatory approval for the
use of nivolumab—an immune checkpoint inhibitor (ICI)—in the first-line treatment of …
use of nivolumab—an immune checkpoint inhibitor (ICI)—in the first-line treatment of …
Long-term outcomes of local resection versus surgical resection for high-risk T1 colorectal cancer: a systematic review and meta-analysis
Y Chen, W Jing, M Chen, Z Wang, J Wu, J Yang… - Gastrointestinal …, 2023 - Elsevier
Background and Aims Patients with T1 colorectal cancer (CRC) are at high risk for lymph
node metastasis and recurrence after local resection (LR) and need surgical resection (SR) …
node metastasis and recurrence after local resection (LR) and need surgical resection (SR) …
Effectiveness of immune checkpoint inhibitors in patients with advanced esophageal squamous cell carcinoma: a meta-analysis including low PD-L1 subgroups
Importance Immune checkpoint inhibitors (ICIs) have improved survival outcomes of patients
with advanced esophageal squamous cell carcinoma in both first-and second-line settings …
with advanced esophageal squamous cell carcinoma in both first-and second-line settings …
First-line systemic therapies for advanced hepatocellular carcinoma: a systematic review and patient-level network meta-analysis
Introduction: Sorafenib was historically the standard of care for advanced hepatocellular
carcinoma (aHCC) until it was superseded by the combination of atezolizumab and …
carcinoma (aHCC) until it was superseded by the combination of atezolizumab and …
Association of low and intermediate combined positive scores with outcomes of treatment with pembrolizumab in patients with recurrent and metastatic head and neck …
Methods| We performed a secondary analysis of Keynote 048 using estimated individual
patient data (IPD). Kaplan-Meier curves were graphically reconstructed3 and IPD for …
patient data (IPD). Kaplan-Meier curves were graphically reconstructed3 and IPD for …
[PDF][PDF] Efficacy of Oral SERDs in the treatment of ER+, HER2-metastatic breast cancer, a stratified analysis of the ESR1 wild type and mutant subgroups
NZH Wong, DWT Yap, RJM Ong, JJ Zhao… - Annals of …, 2023 - annalsofoncology.org
BACKGROUND Oral SERDs are a novel drug class that have been developed to counteract
resistance due to ESR1 mutations. Several SERDs have emerged from phase 2 and 3 trials …
resistance due to ESR1 mutations. Several SERDs have emerged from phase 2 and 3 trials …
The efficacy of immune checkpoint inhibitors on low PD‐L1 cervical cancer: A meta‐analysis
W Chen, N Zhang, Z He, Q Li, Y Wang… - Health Science …, 2024 - Wiley Online Library
Abstract Background and Aims The effectiveness of immune checkpoint inhibitors (ICIs) in
low programmed death ligand 1 (PD‐L1) expression in cervical cancer (CC) patients …
low programmed death ligand 1 (PD‐L1) expression in cervical cancer (CC) patients …
External control arms and data analysis methods in nonrandomized trial of patients with glioblastoma
JJ Mandel, JF de Groot - JAMA oncology, 2023 - jamanetwork.com
To the Editor Liau et al1 report the results of a phase 3 nonrandomized controlled trial of
treatment with autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) for …
treatment with autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L) for …
First-line immune checkpoint inhibitors in low programmed death-ligand 1-expressing population
F Zhang, G Chen, Y Yin, X Chen, R Nie… - Frontiers in …, 2024 - frontiersin.org
Introduction: Inhibitors of programmed cell death 1 (PD1) and its ligand (PDL1) have
exhibited favorable long-term survival in many types of advanced-stage cancer and current …
exhibited favorable long-term survival in many types of advanced-stage cancer and current …
Chemo-immunotherapy in advanced esophageal squamous cell carcinoma: present and future
ZX Wang, RH Xu - Holistic Integrative Oncology, 2023 - Springer
With the recent progress in scientific research, the combination of chemotherapy and PD-1
blockade has become the new standard-of-care first-line treatment for patients with …
blockade has become the new standard-of-care first-line treatment for patients with …