Age-related macular degeneration (AMD) is a complex eye disease underlined by the death
of photoreceptors and degeneration of retinal pigment epithelium (RPE) and choriocapillaris …

Osteoarthritis (OA) is a chronic, debilitating joint disease characterized by progressive
destruction of articular cartilage. For a long time, OA has been considered as a degenerative …

Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death
and is the most common type of liver cancer. Due to the current paucity of drugs for HCC …

Cigarette smoke (CS) affects DNA damage and cellular senescence signaling pathways in
the pathogenesis of chronic obstructive pulmonary disease (COPD). p16INK4a (p16: a …

Cellular senescence is now recognised as one of the hallmarks of ageing. Herein, we
examine current findings on senescence of the vascular endothelium and its impacts on age …

Over 100 putative driver genes that are associated with multiple recurrently altered
pathways were detected in hepatocellular carcinoma (HCC), suggesting that multiple …

The receptor interacting protein kinases 1/3 (RIPK1/3) have emerged as the key mediators
in cell death pathways and inflammatory signaling, whose ubiquitination, phosphorylation …

Cellular senescence is a cell state involved in both physiological and pathological
processes such as age-related diseases and cancer. While the mechanism of senescence is …

Post-transplant lymphoproliferative disorders (PTLD) represent a severe complication in
transplanted patients and Epstein-Barr Virus (EBV) is the main driver. Besides …

Polyphenols, a class of bioactive compounds existing in food and fruit, play an essential role
in anti‐oxidation, anti‐inflammation, anticancer, anti‐atherosclerosis, and antiaging by …