The vascular smooth muscle cell (VSMC) is surrounded by a complex extracellular matrix
that provides and modulates a variety of biochemical and mechanical cues that guide cell …

Arterial disease in CKD patients is characterized by extensive calcification. Evidence has
accumulated pointing to the active and regulated nature of the calcification process …

Hydrogels based on poly (ethylene glycol)(PEG) are of increasing interest for regenerative
medicine applications and are ideal materials to direct cell function due to the ability to …

• Introduction• Components of blood vessel• Principle of vessel engineering• Seeding cells
sources‐Autologous ECs and SMCs‐Embryonic stem cells‐Adult stem cells‐Other cell …

Tissue engineering offers an attractive approach to creating functional small-diameter (< 5
mm) blood vessels by combining autologous cells with a natural and/or synthetic scaffold …

Novel tubular scaffolds of marine source collagen and PLGA fibers were fabricated by freeze
drying and electrospinning processes for vascular grafts. The hybrid scaffolds, composed of …

Blood vessels are subjected in vivo to mechanical forces in a form of radial distention,
encompassing cyclic mechanical strain due to the pulsatile nature of blood flow. Vascular …

Cell mechanical microenvironment (CMM) significantly affects cell behaviors such as
spreading, migration, proliferation and differentiation. However, most studies on cell …

Studies using 2-D cultures have shown that the mechanical properties of the extracellular
matrix (ECM) influence cell migration, spreading, proliferation, and differentiation; however …

The ability to harvest and maintain viable cells from mammalian tissues represented a
critical advance in biomedical research, enabling individual cells to be cultured and studied …