Cholesterol and phosphatidyl inositol 4, 5-bisphosphate (PIP2) are hydrophobic molecules
that regulate protein function in the plasma membrane of all cells. In this review, we discuss …

Although liquid–liquid phase separation of cytoplasmic or nuclear components in cells has
been a major focus in cell biology, it is only recently that the principle of phase separation …

Images of micrometer-scale domains in lipid bilayers have provided the gold standard of
model-free evidence to understand the domains' shapes, sizes, and distributions …

Quantitative differential interference contrast microscopy is demonstrated here as a label-
free method, which is able to image and measure the thickness of lipid bilayers with 0.1 nm …

The interfacing of measurement instrumentation to small computers for the purpose of online
data acquisition has now become standard practice in the modern laboratory. Computerized …

Cholesterol has been conjectured to be a modulator of the amyloid cascade, the mechanism
that produces the amyloid-β (Aβ) peptides implicated in the onset of Alzheimer's disease …

Giant unilamellar vesicles (GUVs) are a widely used model system to interrogate lipid phase
behavior, study biomembrane mechanics, reconstitute membrane proteins, and provide a …

Upon nutrient limitation, budding yeast of Saccharomyces cerevisiae shift from fast growth
(the log stage) to quiescence (the stationary stage). This shift is accompanied by liquid-liquid …

Characterizing the nanoscale dynamic organization within lipid bilayer membranes is
central to our understanding of cell membranes at a molecular level. We investigate phase …

Inorganic nanoparticles (NPs) represent promising examples of engineered nanomaterials,
providing interesting biomedical solutions in several fields, like therapeutics and …