Current evidence on COVID-19 prognostic models is inconsistent and clinical applicability
remains controversial. We performed a systematic review to summarize and critically …

Immune organ failure is frequent in critical illness independent of its cause and has been
acknowledged for a long time. Most patients admitted to the ICU, whether featuring infection …

SARS-CoV-2 is a new coronavirus characterized by a high infection and transmission
capacity. A significant number of patients develop inadequate immune responses that …

Glucocorticoids potently inhibit expression of many inflammatory mediators, and have been
widely used to treat both acute and chronic inflammatory diseases for more than seventy …

COVID-19 is characterized by a broad range of symptoms and disease trajectories.
Understanding the correlation between clinical biomarkers and lung pathology during acute …

Background Evaluating the serum levels of IP-10, MCP-1, MIP-1α, and IL-6 and genotyping
of rs12252 SNP of IFITM3 gene among different categories of COVID-19 patients might aid …

Objective Immune changes play fundamental roles in the pathogenesis and severity of
coronavirus disease 2019 (COVID-19). Previous studies have revealed alterations in …

Thymic stromal lymphopoietin (TSLP) is an epithelium-derived pro-inflammatory cytokine
involved in lung inflammatory responses. Previous studies show conflicting observations in …

Introduction Multisystem inflammatory syndrome in children (MIS-C) is a severe acute
inflammatory reaction to SARS-CoV-2 infection in children. There is a lack of data describing …

Introduction: This systematic review and meta-analysis aimed to determine the correlation
between IL-4 concentrations and COVID-19 severity. Methods: This study was designed as …