Background Protective mechanical ventilation strategies using low tidal volume or high
levels of positive end-expiratory pressure (PEEP) improve outcomes for patients who have …

Background: Community-acquired pneumonia (CAP) is common and often severe. Purpose:
To examine the effect of adjunctive corticosteroid therapy on mortality, morbidity, and …

Importance Experimental data suggest that intravenous vitamin C may attenuate
inflammation and vascular injury associated with sepsis and acute respiratory distress …

Rationale: Estimates of the incidence of the acute respiratory distress syndrome (ARDS) in
high-and middle-income countries vary from 10.1 to 86.2 per 100,000 person-years in the …

Acute respiratory distress syndrome (ARDS) is a common disease entity in critical care
medicine and is still associated with a high mortality. Because of the heterogeneous …

Innate immunity normally provides excellent defence against invading microorganisms.
Acute inflammation is a form of innate immune defence and represents one of the primary …

Background Over the last decade, several studies have suggested that survival rates for
patients with acute lung injury (ALI) or ARDS may have improved. We performed a …

Purpose Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for patients
with acute respiratory distress syndrome (ARDS). The aim of this study was to evaluate …

Objective: Acute respiratory distress syndrome might be associated with an increase in
extravascular lung water index and pulmonary vascular permeability index, which can be …

Objective: Studies from single centers have suggested that mortality from acute lung injury
(ALI) has declined over time. However, recent trends in ALI mortality from centers across the …