Prognosis of chronic Chagas heart disease and other pending clinical challenges

RM Torres, D Correia, MCP Nunes… - Memórias do Instituto …, 2022 - SciELO Brasil
In this chapter, the main prognostic markers of Chagas heart disease are addressed, with an
emphasis on the most recent findings and questions, establishing the basis for a broad …

Understanding the oral transmission of Trypanosoma cruzi as a veterinary and medical foodborne zoonosis

N Velásquez-Ortiz, JD Ramírez - Research in veterinary science, 2020 - Elsevier
Chagas disease is a neglected tropical disease transmitted by the protozoan Trypanosoma
cruzi that lately has been highlighted because several outbreaks attributed to oral …

SBC guideline on the diagnosis and treatment of patients with cardiomyopathy of chagas disease–2023

JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos Brasileiros …, 2023 - SciELO Brasil
SciELO - Brazil - Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e Tratamento …

Molecular and clinical aspects of chronic manifestations in Chagas disease: a state-of-the-art review

GJ Medina-Rincón, S Gallo-Bernal, PA Jiménez… - Pathogens, 2021 - mdpi.com
Chronic manifestations of Chagas disease present as disabling and life-threatening
conditions affecting mainly the cardiovascular and gastrointestinal systems. Although …

Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas–2023

JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos Brasileiros …, 2023 - SciELO Brasil
A DC (tripanossomíase americana) é entidade mórbida transmissível, potencialmente fatal,
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …

Experimental Chagas disease-induced perturbations of the fecal microbiome and metabolome

LI McCall, A Tripathi, F Vargas, R Knight… - PLoS neglected …, 2018 - journals.plos.org
Trypanosoma cruzi parasites are the causative agents of Chagas disease. These parasites
infect cardiac and gastrointestinal tissues, leading to local inflammation and tissue damage …

Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD)

S Clayton, E Cauble, A Kumar, N Patil, D Ledford… - BMC …, 2019 - Springer
An elevation of serum inflammatory biomarkers in achalasia patients compared with controls
recently was demonstrated. It has not been determined whether the elevation of …

Engineering Oral and Parenteral Amorphous Amphotericin B Formulations against Experimental Trypanosoma cruzi Infections

M Rolon, DR Serrano, A Lalatsa… - Molecular …, 2017 - ACS Publications
Chagas disease (CD) is a parasitic zoonosis endemic in most mainland countries of Central
and South America affecting nearly 10 million people, with 100 million people at high risk of …

Neuronal parasitism, early myenteric neurons depopulation and continuous axonal networking damage as underlying mechanisms of the experimental intestinal …

MF Ricci, SR Béla, MM Moraes, MT Bahia… - Frontiers in Cellular …, 2020 - frontiersin.org
There is a growing consensus that the balance between the persistence of infection and the
host immune response is crucial for chronification of Chagas heart disease. Extrapolation for …

Entamoeba histolytica Calreticulin Induces the Expression of Cytokines in Peripheral Blood Mononuclear Cells Isolated From Patients With Amebic Liver Abscess

E Gonzalez Rivas, C Ximenez… - Frontiers in cellular …, 2018 - frontiersin.org
Calreticulin (CRT) is a highly conserved protein in the endoplasmic reticulum that plays
important roles in the regulation of key cellular functions. Little is known about the …