[HTML][HTML] The role of interleukins in recurrent implantation failure: a comprehensive review of the literature

K Pantos, S Grigoriadis, E Maziotis, K Pistola… - International journal of …, 2022 - mdpi.com
Recurrent implantation failure (RIF) is a multifactorial condition affecting 10–15% of in vitro
fertilization (IVF) couples. Data suggest that functional dysregulation of the endometrial …

Immune alterations in recurrent implantation failure

N Mukherjee, R Sharma, D Modi - American Journal of …, 2023 - Wiley Online Library
A failure to achieve pregnancy after three or more embryo transfer cycles with high‐quality
blastocysts is referred to as recurrent implantation failure (RIF). RIF can be due to altered …

Endometrial receptivity and embryo implantation in carnivores—commonalities and differences with other mammalian species

EE Paulson, P Comizzoli - Biology of reproduction, 2021 - academic.oup.com
Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

[HTML][HTML] Clinical relevance of vaginal and endometrial microbiome investigation in women with repeated implantation failure and recurrent pregnancy loss

X Gao, YV Louwers, JSE Laven… - International Journal of …, 2024 - mdpi.com
Recent studies have investigated if and how the vaginal and endometrial microbiome might
affect endometrial receptivity and reproductive health. Although there is no consensus on …

[HTML][HTML] Identification of MARK2, CCDC71, GATA2, and KLRC3 as candidate diagnostic genes and potential therapeutic targets for repeated implantation failure with …

M Zhang, T Ge, Y Zhang, X La - Frontiers in Immunology, 2023 - frontiersin.org
Background Antiphospholipid syndrome (APS) is a group of clinical syndromes of
thrombosis or adverse pregnancy outcomes caused by antiphospholipid antibodies, which …

[HTML][HTML] Identification of potential biomarkers and immune infiltration characteristics in recurrent implantation failure using bioinformatics analysis

ZZ Lai, J Zhang, WJ Zhou, JW Shi, HL Yang… - Frontiers in …, 2023 - frontiersin.org
Introduction Recurrent implantation failure (RIF) is a frustrating challenge because the cause
is unknown. The current study aims to identify differentially expressed genes (DEGs) in the …

Ageing, a modulator of human endometrial stromal cell proliferation and decidualization: a role for implantation?

A Berdiaki, S Zafeiropoulou, F Makrygiannakis… - Reproductive …, 2022 - Elsevier
Research question Does ageing affect endometrial stromal cell function and gene
expression involved in decidualization? Design Stromal cells were isolated and cultured …

[HTML][HTML] Recurrent implantation failure: bioinformatic discovery of biomarkers and identification of metabolic subtypes

Y Fan, C Shi, N Huang, F Fang, L Tian… - International Journal of …, 2023 - mdpi.com
Recurrent implantation failure (RIF) is a challenging scenario from different standpoints. This
study aimed to investigate its correlation with the endometrial metabolic characteristics …

[HTML][HTML] Immune system cells modulation in patients with reproductive issues: A systematic review approach

GA de Moura, YM Rocha, FLD Moura… - JBRA Assisted …, 2024 - ncbi.nlm.nih.gov
The aim of this study was to carry out a systematic literature review to investigate the main
immune cells responsible for implantation failures. We selected papers from PubMed …

Repeated implantation failure is associated with increased Th17/Treg cell ratio, during the secretory phase of the human endometrium

A Berdiaki, E Vergadi, F Makrygiannakis… - Journal of Reproductive …, 2024 - Elsevier
Repeated implantation failure (RIF) is a significant limiting factor in assisted reproduction.
Chronic endometrial inflammation has been noted in RIF women, therefore we sought to …