Mechanistic pathogenesis of endothelial dysfunction in diabetic nephropathy and retinopathy
J Yang, Z Liu - Frontiers in endocrinology, 2022 - frontiersin.org
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of
diabetes. Microvascular endothelial cells are thought to be the major targets of …
diabetes. Microvascular endothelial cells are thought to be the major targets of …
Complexities of the glomerular basement membrane
The glomerular basement membrane (GBM) is a key component of the glomerular capillary
wall and is essential for kidney filtration. The major components of the GBM include …
wall and is essential for kidney filtration. The major components of the GBM include …
A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations
R Jayadev, MRPT Morais, JM Ellingford… - Science …, 2022 - science.org
Basement membranes (BMs) are ubiquitous extracellular matrices whose composition
remains elusive, limiting our understanding of BM regulation and function. By developing a …
remains elusive, limiting our understanding of BM regulation and function. By developing a …
Subcellular connectomic analyses of energy networks in striated muscle
Mapping biological circuit connectivity has revolutionized our understanding of structure-
function relationships. Although connectomic analyses have primarily focused on neural …
function relationships. Although connectomic analyses have primarily focused on neural …
Nephrin signaling in the podocyte: an updated view of signal regulation at the slit diaphragm and beyond
Podocytes are a major component of the glomerular blood filtration barrier, and alterations to
the morphology of their unique actin-based foot processes (FP) are a common feature of …
the morphology of their unique actin-based foot processes (FP) are a common feature of …
Alport syndrome and Pierson syndrome: diseases of the glomerular basement membrane
SD Funk, MH Lin, JH Miner - Matrix Biology, 2018 - Elsevier
The glomerular basement membrane (GBM) is an important component of the kidney's
glomerular filtration barrier. Like all basement membranes, the GBM contains type IV …
glomerular filtration barrier. Like all basement membranes, the GBM contains type IV …
[HTML][HTML] Genetic basis of type IV collagen disorders of the kidney
C Quinlan, MN Rheault - Clinical Journal of the American Society …, 2021 - journals.lww.com
The glomerular basement membrane is a vital component of the filtration barrier of the
kidney and is primarily composed of a highly structured matrix of type IV collagen. Specific …
kidney and is primarily composed of a highly structured matrix of type IV collagen. Specific …
New insights into podocyte biology in glomerular health and disease
S Assady, N Wanner, KL Skorecki… - Journal of the American …, 2017 - journals.lww.com
Podocyte and glomerular research is center stage for the development of improved
preventive and therapeutic strategies for chronic progressive kidney diseases. Held April 3 …
preventive and therapeutic strategies for chronic progressive kidney diseases. Held April 3 …
[HTML][HTML] From podocyte biology to novel cures for glomerular disease
E Torban, F Braun, N Wanner, T Takano, PR Goodyer… - Kidney international, 2019 - Elsevier
The podocyte is a key component of the glomerular filtration barrier. Podocyte dysfunction is
central to the underlying pathophysiology of many common glomerular diseases, including …
central to the underlying pathophysiology of many common glomerular diseases, including …
Serial block face‐scanning electron microscopy as a burgeoning technology
Serial block face scanning electron microscopy (SBF‐SEM), also referred to as serial block‐
face electron microscopy, is an advanced ultrastructural imaging technique that enables …
face electron microscopy, is an advanced ultrastructural imaging technique that enables …