[HTML][HTML] The past, present and future of anti-malarial medicines
Great progress has been made in recent years to reduce the high level of suffering caused
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …
Biologically active quinoline and quinazoline alkaloids part I
XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …
compounds, have attracted tremendous attention from researchers worldwide since the 19th …
Sulfoximines as rising stars in modern drug discovery? Current status and perspective on an emerging functional group in medicinal chemistry
Sulfoximines have been largely disregarded in medicinal chemistry for a long time.
However, recently, they have risen to the apparent level of stardom on the drug discovery …
However, recently, they have risen to the apparent level of stardom on the drug discovery …
Triazole derivatives and their antiplasmodial and antimalarial activities
XM Chu, C Wang, WL Wang, LL Liang, W Liu… - European journal of …, 2019 - Elsevier
Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …
Recent progress in the development of new antimalarial drugs with novel targets
TM Belete - Drug design, development and therapy, 2020 - Taylor & Francis
Malaria is a major global health problem that causes significant mortality and morbidity
annually. The therapeutic options are scarce and massively challenged by the emergence of …
annually. The therapeutic options are scarce and massively challenged by the emergence of …
Recent update on antibacterial and antifungal activity of quinoline scaffolds
A Dorababu - Archiv der Pharmazie, 2021 - Wiley Online Library
Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …
Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents
Malaria remains one of the major health problems worldwide. The lack of an effective
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …
Radical transformations towards the synthesis of quinoline: A review
Quinoline is considered one of the most ubiquitous heterocycles due to its engaging
biological activities and synthetic utility over organic transformations. Over the past few …
biological activities and synthetic utility over organic transformations. Over the past few …
[HTML][HTML] Plants as sources of natural and recombinant antimalaria agents
Malaria is one of the severe infectious diseases that has victimized about half a civilization
billion people each year worldwide. The application of long-lasting insecticides is the main …
billion people each year worldwide. The application of long-lasting insecticides is the main …
Quinoline‐based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors
A series of substituted quinolines was screened for their antiproliferative, cytotoxic,
antibacterial activities, DNA/protein binding affinity, and anticholinergic properties by using …
antibacterial activities, DNA/protein binding affinity, and anticholinergic properties by using …