[HTML][HTML] The past, present and future of anti-malarial medicines

EG Tse, M Korsik, MH Todd - Malaria journal, 2019 - Springer
Great progress has been made in recent years to reduce the high level of suffering caused
by malaria worldwide. Notably, the use of insecticide-treated mosquito nets for malaria …

Biologically active quinoline and quinazoline alkaloids part I

XF Shang, SL Morris‐Natschke, YQ Liu… - Medicinal research …, 2018 - Wiley Online Library
Quinoline and quinazoline alkaloids, two important classes of N‐based heterocyclic
compounds, have attracted tremendous attention from researchers worldwide since the 19th …

Sulfoximines as rising stars in modern drug discovery? Current status and perspective on an emerging functional group in medicinal chemistry

P Mäder, L Kattner - Journal of Medicinal Chemistry, 2020 - ACS Publications
Sulfoximines have been largely disregarded in medicinal chemistry for a long time.
However, recently, they have risen to the apparent level of stardom on the drug discovery …

Triazole derivatives and their antiplasmodial and antimalarial activities

XM Chu, C Wang, WL Wang, LL Liang, W Liu… - European journal of …, 2019 - Elsevier
Malaria, caused by protozoan parasites of the genus Plasmodium especially by the most
prevalent parasite Plasmodium falciparum, represents one of the most devastating and …

Recent progress in the development of new antimalarial drugs with novel targets

TM Belete - Drug design, development and therapy, 2020 - Taylor & Francis
Malaria is a major global health problem that causes significant mortality and morbidity
annually. The therapeutic options are scarce and massively challenged by the emergence of …

Recent update on antibacterial and antifungal activity of quinoline scaffolds

A Dorababu - Archiv der Pharmazie, 2021 - Wiley Online Library
Although most of the heterocycles have been reported to possess a significant
pharmacological activity, only a few of them, namely quinoline derivatives, have exhibited …

Design and synthesis of harmiquins, harmine and chloroquine hybrids as potent antiplasmodial agents

G Poje, LP de Carvalho, J Held, D Moita… - European journal of …, 2022 - Elsevier
Malaria remains one of the major health problems worldwide. The lack of an effective
vaccine and the increasing resistance of Plasmodium to the approved antimalarial drugs …

Radical transformations towards the synthesis of quinoline: A review

C Teja, FRN Khan - Chemistry–An Asian Journal, 2020 - Wiley Online Library
Quinoline is considered one of the most ubiquitous heterocycles due to its engaging
biological activities and synthetic utility over organic transformations. Over the past few …

[HTML][HTML] Plants as sources of natural and recombinant antimalaria agents

P Habibi, Y Shi, M Fatima Grossi-de-Sa, I Khan - Molecular biotechnology, 2022 - Springer
Malaria is one of the severe infectious diseases that has victimized about half a civilization
billion people each year worldwide. The application of long-lasting insecticides is the main …

Quinoline‐based promising anticancer and antibacterial agents, and some metabolic enzyme inhibitors

S Ökten, A Aydın, ÜM Koçyiğit, O Çakmak… - Archiv der …, 2020 - Wiley Online Library
A series of substituted quinolines was screened for their antiproliferative, cytotoxic,
antibacterial activities, DNA/protein binding affinity, and anticholinergic properties by using …