Heart failure is a significant public health burden that differentially impacts women. Important
sex-and gender-based differences in HF risk factors, presentation, and treatment exist, and …

Over 38.4 million people were living with HIV globally in 2021. The HIV continuum includes
HIV testing, diagnosis, linkage to combined antiretroviral therapy (cART), and retention in …

Aims In AFFIRM‐AHF, intravenous ferric carboxymaltose (FCM) reduced heart failure (HF)
hospitalisations and improved quality of life versus placebo in iron‐deficient patients …

Introduction In trials, subgroup analyses are used to examine whether treatment effects differ
by important patient characteristics. However, which subgroups are most commonly reported …

Background Heart failure (HF) is a common condition that imposes a significant burden on
healthcare systems. We aimed to identify subgroups of patients with heart failure admitted to …

Pulmonary hypertension (PH) treatment decisions are driven by the results of randomized
controlled trials (RCTs). Subgroup analyses are often performed to assess whether the …

Context and objective Randomised controlled trials (hereafter, trials) are widely regarded as
the gold standard for evaluating treatment efficacy in medical interventions. They employ …

We appreciate the interest shown by Shaw et al. in our manuscript. The authors raise
several important points that we hope to address. First, the authors ask us to define what is …

Background. Pulmonary hypertension (PH) treatment decisions are driven by randomized
controlled trials (RCTs) results. Subgroup analyses are often performed to assess whether …