Assessing the potential contribution of in silico studies in discovering drug candidates that interact with various SARS-CoV-2 receptors

AGA Mushebenge, SC Ugbaja, NA Mbatha… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has spurred intense research efforts to identify effective treatments
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …

An Update of Carbazole Treatment Strategies for COVID-19 Infection

MG Bonomo, A Caruso, H El-Kashef, G Salzano… - Applied Sciences, 2023 - mdpi.com
The Coronavirus disease 2019 (COVID-19) outbreak was declared by the World Health
Organization (WHO) in March 2020 to be a pandemic and many drugs used at the beginning …

Intermolecular interaction study of Favipiravir-Uracil biomolecular complex using vibrational spectroscopic techniques and computational methods

PS Singh, TG Devi - Journal of Molecular Structure, 2024 - Elsevier
The present work is carried out to understand the molecular interaction between Favipiravir
(antiviral drug) and Uracil (Nucleobase) using computational and experimental methods …

Favipiravir Analogues as Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase, Combined Quantum Chemical Modeling, Quantitative Structure–Property …

M Latosińska, JN Latosińska - Molecules, 2024 - mdpi.com
Our study was motivated by the urgent need to develop or improve antivirals for effective
therapy targeting RNA viruses. We hypothesized that analogues of favipiravir (FVP), an …

Drug Synergism of Anticancer Action in Combination with Favipiravir and Paclitaxel on Neuroblastoma Cells

H Turkez, ME Arslan, H Selvitopi, A Kadi, S Oner… - Medicina, 2023 - mdpi.com
Background and Objectives: Favipiravir (FPV) is an antiviral medication and has an
inhibitory effect on Cytochrome P450 (CYP2C8) protein, which is mainly involved in drug …

Implications of antibiotics and antimicrobial resistance development during COVID-19: questing genomic surveillance for a balancing act

V Yadav, K Yadav, R Sehgal, R Islam - Genomic Surveillance and …, 2023 - Elsevier
The COVID-19 pandemic has jolted the health system globally and a paucity of specific
drugs and/or vaccine hesitancy led clinicians to indiscriminately use antibiotics …

[图书][B] Genomic Surveillance and Pandemic Preparedness

R Pandey - 2023 - books.google.com
Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in
where, how, and why genomic surveillance may be applied. Drawing heavily from the …

[PDF][PDF] Exploring The Inhibition Potential of FDA Approved Beta-Lactams and Their Newly Designed Derivatives Against Mycobacterium Tuberculosis: Molecular …

K Bux, H Ahmed, FK Usman, B Cem - primepubmed.com
Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis is one of the most
prevalent diseases with an approximate of 10 million people having suffered from it in the …