[HTML][HTML] Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies
The incidence and prevalence of diabetes mellitus is rapidly increasing worldwide at an
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …
alarming rate. Type 2 diabetes mellitus (T2DM) is the most prevalent form of diabetes …
[HTML][HTML] Diabetes, cardiovascular disease and the microcirculation
WD Strain, PM Paldánius - Cardiovascular diabetology, 2018 - Springer
Cardiovascular disease (CVD) is the leading cause of mortality in people with type 2
diabetes mellitus (T2DM), yet a significant proportion of the disease burden cannot be …
diabetes mellitus (T2DM), yet a significant proportion of the disease burden cannot be …
[HTML][HTML] Endothelial dysfunction—a major mediator of diabetic vascular disease
CM Sena, AM Pereira, R Seiça - … et Biophysica Acta (BBA)-molecular basis …, 2013 - Elsevier
The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
vascular tone and structure. Endothelial cells produce a wide range of factors that also …
Diabetes and hypertension: the bad companions
E Ferrannini, WC Cushman - The Lancet, 2012 - thelancet.com
High blood pressure is reported in over two-thirds of patients with type 2 diabetes, and its
development coincides with the development of hyperglycaemia. Many pathophysiological …
development coincides with the development of hyperglycaemia. Many pathophysiological …
Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
N Esser, S Legrand-Poels, J Piette, AJ Scheen… - Diabetes research and …, 2014 - Elsevier
It is recognized that a chronic low-grade inflammation and an activation of the immune
system are involved in the pathogenesis of obesity-related insulin resistance and type 2 …
system are involved in the pathogenesis of obesity-related insulin resistance and type 2 …
Diabetes mellitus and periodontal diseases
BL Mealey, TW Oates - Journal of periodontology, 2006 - Wiley Online Library
Background: The purpose of this review is to provide the reader with practical knowledge
concerning the relationship between diabetes mellitus and periodontal diseases. Over 200 …
concerning the relationship between diabetes mellitus and periodontal diseases. Over 200 …
Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalanced coagulation in development of diabetes and its complications
RB Goldberg - The Journal of Clinical Endocrinology & …, 2009 - academic.oup.com
Context: Recent developments indicate that pathophysiological mechanisms leading to β-
cell damage, insulin resistance, and the vascular complications of diabetes include an …
cell damage, insulin resistance, and the vascular complications of diabetes include an …
[PDF][PDF] Empagliflozin and dapagliflozin reduce ROS generation and restore NO bioavailability in tumor necrosis factor α-stimulated human coronary arterial endothelial …
L Uthman, A Homayr, RP Juni, EL Spin… - Cell Physiol …, 2019 - cellphysiolbiochem.com
Abstract Background/Aims: Heart failure is characterized by chronic low-grade vascular
inflammation, which in itself can lead to endothelial dysfunction. Clinical trials showed …
inflammation, which in itself can lead to endothelial dysfunction. Clinical trials showed …
Cardiovascular disease in type 2 diabetes from population to man to mechanisms: the Kelly West Award Lecture 2008
M Laakso - Diabetes care, 2010 - Am Diabetes Assoc
Epidemic of diabetes, affecting about 3–5% of Western populations, is one of the main
threats to human health in the 21st century (1). Changes in the human environment …
threats to human health in the 21st century (1). Changes in the human environment …
Diabetes mellitus as a prothrombotic condition
PJ Grant - Journal of internal medicine, 2007 - Wiley Online Library
Diabetes mellitus (DM) is characterized by fasting hyperglycaemia and a high risk of
atherothrombotic disorders affecting the coronary, cerebral and peripheral arterial trees. The …
atherothrombotic disorders affecting the coronary, cerebral and peripheral arterial trees. The …