Magnetic resonance spectroscopy with transcranial direct current stimulation to explore the underlying biochemical and physiological mechanism of the human brain …

CH Choi, E Iordanishvili, NJ Shah… - Human brain …, 2021 - Wiley Online Library
A large body of molecular and neurophysiological evidence connects synaptic plasticity to
specific functions and energy metabolism in particular areas of the brain. Furthermore …

Effect of high‐intensity interval training on hippocampal metabolism in older adolescents

SR Valkenborghs, CH Hillman, O Al‐Iedani… - …, 2022 - Wiley Online Library
Although well‐evidenced in older adults, the effects of exercise on the hippocampus in youth
are relatively unknown. This study examined the impact of a 6‐month school‐based physical …

13C-Stable isotope resolved metabolomics uncovers dynamic biochemical landscape of gut microbiome-host organ communications in mice

X Xiao, Y Zhou, X Li, J Jin, J Durham, Z Ye, Y Wang… - Microbiome, 2024 - Springer
Background Gut microbiome metabolites are important modulators of host health and
disease. However, the overall metabolic potential of the gut microbiome and interactions …

Peak ependymal cell stretch overlaps with the onset locations of periventricular white matter lesions

VL Visser, H Rusinek, J Weickenmeier - Scientific Reports, 2021 - nature.com
Deep and periventricular white matter hyperintensities (dWMH/pvWMH) are bright
appearing white matter tissue lesions in T2-weighted fluid attenuated inversion recovery …

White matter plasticity in anxiety: disruption of neural network synchronization during threat-safety discrimination

J Liu, E Likhtik, AD Shereen… - Frontiers in Cellular …, 2020 - frontiersin.org
Recent evidence highlighted the importance of white matter tracts in typical and atypical
behaviors. White matter dynamically changes in response to learning, stress, and social …

Impact of lifetime stressor exposure on neuroenergetics in schizophrenia spectrum disorders

J Chiappelli, A Savransky, Y Ma, S Gao… - Schizophrenia …, 2024 - Elsevier
N-acetylasparate and lactate are two prominent brain metabolites closely related to
mitochondrial functioning. Prior research revealing lower levels of NAA and higher levels of …

Covariance matrix estimation for high-throughput biomedical data with interconnected communities

Y Yang, C Chen, S Chen - The American Statistician, 2024 - Taylor & Francis
Estimating a covariance matrix is central to high-dimensional data analysis. Empirical
analyses of high-dimensional biomedical data, including genomics, proteomics …

Serine, N-acetylaspartate differentiate adolescents with juvenile idiopathic arthritis compared with healthy controls: a metabolomics cross-sectional study

KA Lewis, N Osier, R Carrasco, J Chiou, P Carter… - Pediatric …, 2022 - Springer
Background In comparison with the general population, adolescents with juvenile idiopathic
arthritis (JIA) are at higher risk for morbidity and mortality. However, limited evidence is …

[图书][B] Metabolic Systems Dyshomeostases Characterize Alzheimer's Disease: Diverse Plasma Metabolomic Evidence from LOAD, DS-AD, and ADAD

TJ Gross - 2022 - search.proquest.com
Alzheimer's disease (AD) has proven remarkably refractory to proposed and approved
therapies, none of which has strongly demonstrated the capability to halt, sustainedly …

[图书][B] Development Of Rapid High-Resolution MR Spectroscopic imaging in the human brain

SV Senthil - 2022 - search.proquest.com
Abstract Proton Magnetic Resonance Spectroscopy (1H MRS) is a specialised non-invasive
modality for identifying and quantifying tissue metabolite concentrations in-vivo. This …