NANOBODIES®: A Review of Generation, Diagnostics and Therapeutics

B Jin, S Odongo, M Radwanska, S Magez - International journal of …, 2023 - mdpi.com
NANOBODY®(a registered trademark of Ablynx NV) molecules (Nbs), also referred to as
single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG …

Discovery of nanobodies: a comprehensive review of their applications and potential over the past five years

E Alexander, KW Leong - Journal of Nanobiotechnology, 2024 - Springer
Nanobodies (Nbs) are antibody fragments derived from heavy-chain-only IgG antibodies
found in the Camelidae family as well as cartilaginous fish. Their unique structural and …

Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis

R Liu, M Zhu, J Chen, J Gai, J Huang… - International Journal …, 2023 - Taylor & Francis
Background No agents are currently available for the treatment or reversal of liver fibrosis.
Novel antifibrotic therapies for chronic liver diseases are thus urgently needed. Connective …

A humanized trivalent Nectin-4-targeting nanobody drug conjugate displays potent antitumor activity in gastric cancer

Y Wu, M Zhu, B Sun, Y Chen, Y Huang, J Gai… - Journal of …, 2024 - Springer
Background Gastric cancer represents a highly lethal malignancy with an elevated mortality
rate among cancer patients, coupled with a suboptimal postoperative survival prognosis …

[HTML][HTML] Nanobody-as Versatile Tool Emerging in Autoimmune Diseases

L Wang, R Luo, W Zhang, H Jiang, Y Yu, W Zhou… - Smart Materials in …, 2024 - Elsevier
Nanobody (Nb) is derived from the variable domain of heavy-chain antibody (HCAb),
naturally displaying notable properties like nano-scale size, exceptional stability, high …

[HTML][HTML] Single-Domain Antibodies—Novel Tools to Study and Treat Allergies

I Zettl, C Bauernfeind, J Kollárová, S Flicker - International Journal of …, 2024 - mdpi.com
IgE-mediated allergies represent a major health problem in the modern world. Apart from
allergen-specific immunotherapy (AIT), the only disease-modifying treatment, researchers …

High performance production process development and scale-up of an anti-TSLP nanobody

X Li, P Qiao, Y Zhang, G Liu, M Zhu, J Gai… - Protein Expression and …, 2024 - Elsevier
Nanobodies (Nbs) represent a class of single-domain antibodies with great potential
application value across diverse biotechnology fields, including therapy and diagnostics …

Mechanisms underlying the efficacy and safety of IgG, antibody fragments, and design immune biologics

A De Marco - Journal of Allergy and Clinical Immunology, 2023 - jacionline.org
A total of 133 therapeutic mAbs have been approved for the European market (https://www.
pei. de/DE/arzneimittel/anti koerper/monoklonale-antikoerper/monoklonale-antikoerper …

Nanoantikorların Genel Özellikleri/Tanı ve Tedavide Kullanımları: Geleneksel Derleme.

T SALMAN… - Journal of Literature …, 2024 - search.ebscohost.com
Hedefleme amacıyla tedavilerde kullanılan geleneksel antikorlar, kanser başta olmak çeşitli
hastalıklarda önemli başarılar sağlamıştır. Ancak büyük boyutları ve buna bağlı olarak kısıtlı …

[引用][C] Znanje odraslih pacientov z astmo o pravilni uporabi vdihovalnikov: magistrska naloga

S Bilkan - 2023 - repozitorij.upr.si
Asthma is one of the most common chronic diseases that is widespread in the world. It is an
immune-mediated inflammatory disease with intermittent and reversible narrowing of the …