Human diseases, particularly infectious diseases and cancers, pose unprecedented
challenges to public health security and the global economy. The development and …

Zoonotic viruses continually pose a pandemic threat. Infection of humans with viruses for
which we typically have little or no prior immunity can result in epidemics with high morbidity …

Although one member of the poxvirus family, variola virus, has caused one of the most
devastating human infections worldwide, smallpox, the knowledge gained over the last 30 …

Background: The lack of effective vaccines against Ebola virus initiates a search for new
approaches to overcoming this problem. The aim of the study was to design artificial …

Background: According to current data, an effective Ebola virus vaccine should induce both
humoral and T-cell immunity. In this work, we focused our efforts on methods for delivering …

Vaccinations are a crucial intervention in combating infectious diseases. The three
neurotropic Alphaviruses, Eastern (EEEV), Venezuelan (VEEV), and Western (WEEV) …

There is a crucial need for an improved H3N2 influenza virus vaccine due to low vaccine
efficacy rates and increased morbidity and mortality associated with H3N2-dominated …

Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg
virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional …

Vaccinia virus has been used as a smallpox vaccine. Now that smallpox has been
eradicated, the vaccinia virus is expected to be used as a bioterrorism countermeasure and …

Influenza A virus infection in swine impacts the agricultural industry in addition to its zoonotic
potential. Here, we utilize epigraph, a computational algorithm, to design a universal swine …