Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy
TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …
Pathogenicity and virulence of Mycobacterium tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, an infectious
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
disease with one of the highest morbidity and mortality rates worldwide. Leveraging its …
The reactive oxygen species in macrophage polarization: reflecting its dual role in progression and treatment of human diseases
High heterogeneity of macrophage is associated with its functions in polarization to different
functional phenotypes depending on environmental cues. Macrophages remain in balanced …
functional phenotypes depending on environmental cues. Macrophages remain in balanced …
ESX‐1 and phthiocerol dimycocerosates of Mycobacterium tuberculosis act in concert to cause phagosomal rupture and host cell apoptosis
J Augenstreich, A Arbues, R Simeone… - Cellular …, 2017 - Wiley Online Library
Although phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium
tuberculosis (Mtb), the causative agent of human tuberculosis, little is known about their …
tuberculosis (Mtb), the causative agent of human tuberculosis, little is known about their …
Role of apoptosis and autophagy in tuberculosis
A Lam, R Prabhu, CM Gross… - … of Physiology-Lung …, 2017 - journals.physiology.org
Tuberculosis (TB) is one of the oldest known human diseases and is transmitted by the
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
bacteria Mycobacterium tuberculosis (Mtb). TB has a rich history with evidence of TB …
Insights into the role of endoplasmic reticulum stress in infectious diseases
JA Choi, CH Song - Frontiers in immunology, 2020 - frontiersin.org
The endoplasmic reticulum (ER) is the major organelle in the cell for protein folding and
plays an important role in cellular functions. The unfolded protein response (UPR) is …
plays an important role in cellular functions. The unfolded protein response (UPR) is …
The PGRS domain of Mycobacterium tuberculosis PE_PGRS protein Rv0297 is involved in endoplasmic reticulum stress-mediated apoptosis through toll-like receptor …
The genome of Mycobacterium tuberculosis, the causal organism of tuberculosis (TB),
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …
encodes a unique protein family known as the PE/PPE/PGRS family, present exclusively in …
Endoplasmic reticulum-localized two-photon-absorbing boron dipyrromethenes as advanced photosensitizers for photodynamic therapy
Two advanced boron dipyrromethene (BODIPY) based photosensitizers have been
synthesized and characterized. With a glibenclamide analogous moiety, these compounds …
synthesized and characterized. With a glibenclamide analogous moiety, these compounds …
Role of C-terminal domain of Mycobacterium tuberculosis PE6 (Rv0335c) protein in host mitochondrial stress and macrophage apoptosis
PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
PE_PGRS45 (Rv2615c) protein of Mycobacterium tuberculosis perturbs mitochondria of macrophages
The PE_PGRS proteins have coevolved with the antigenic ESX‐V secretory system and are
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …