Biosensors for detection of human placental pathologies: a review of emerging technologies and current trends
Substantial growth in the biosensor research has enabled novel, sensitive and point-of-care
diagnosis of human diseases in the last decade. This paper presents an overview of the …
diagnosis of human diseases in the last decade. This paper presents an overview of the …
Malaria Parasite Plasmodium falciparum Proteins on the Surface of Infected Erythrocytes as Targets for Novel Drug Discovery
AV Oleinikov - Biochemistry (Moscow), 2022 - Springer
Specific adhesion (sequestration) of Plasmodium falciparum parasite-infected erythrocytes
(IEs) in deep vascular beds can cause severe complications resulting in death. This review …
(IEs) in deep vascular beds can cause severe complications resulting in death. This review …
Enhanced Antimalarial and Antisequestration Activity of Methoxybenzenesulfonate-Modified Biopolymers and Nanoparticles for Tackling Severe Malaria
Severe malaria is a life-threatening condition that is associated with a high mortality. Severe
Plasmodium falciparum infections are mediated primarily by high parasitemia and binding of …
Plasmodium falciparum infections are mediated primarily by high parasitemia and binding of …
Rational designing of peptide-ligand conjugates-based immunotherapy for the treatment of complicated malaria
Aims Malaria deaths occur primarily due to complicated malaria associated with the
sequestration of Plasmodium falciparum-infected erythrocyte (Pf IE) in the capillary …
sequestration of Plasmodium falciparum-infected erythrocyte (Pf IE) in the capillary …
Plasmodium falciparum infected erythrocytes can bind to host receptors integrins αVβ3 and αVβ6 through DBLδ1_D4 domain of PFL2665c PfEMP1 protein
O Chesnokov, J Merritt, SO Tcherniuk, N Milman… - Scientific reports, 2018 - nature.com
Major complications and mortality from Plasmodium falciparum malaria are associated with
cytoadhesion of parasite-infected erythrocytes (IE). The main parasite ligands for …
cytoadhesion of parasite-infected erythrocytes (IE). The main parasite ligands for …
Small Molecule Compounds Identified from Mixture-Based Library Inhibit Binding between Plasmodium falciparum Infected Erythrocytes and Endothelial Receptor …
O Chesnokov, P Visitdesotrakul, K Kalani… - International journal of …, 2021 - mdpi.com
Specific adhesion of P. falciparum parasite-infected erythrocytes (IE) in deep vascular beds
can result in severe complications, such as cerebral malaria, placental malaria, respiratory …
can result in severe complications, such as cerebral malaria, placental malaria, respiratory …
Rosette-Disrupting Effect of an Anti-Plasmodial Compound for the Potential Treatment of Plasmodium falciparum Malaria Complications
JH Ch'ng, K Moll, MP Quintana, SCL Chan… - Scientific reports, 2016 - nature.com
The spread of artemisinin-resistant parasites could lead to higher incidence of patients with
malaria complications. However, there are no current treatments that directly dislodge …
malaria complications. However, there are no current treatments that directly dislodge …
Malaria parasite proteins and their role in alteration of the structure and function of red blood cells
Malaria, caused by Plasmodium spp., continues to be a major threat to human health and a
significant cause of socioeconomic hardship in many countries. Almost half of the world's …
significant cause of socioeconomic hardship in many countries. Almost half of the world's …
IgG acquisition against PfEMP1 PF11_0521 domain cassette DC13, DBLβ3_D4 domain, and peptides located within these constructs in children with cerebral malaria
C Badaut, P Visitdesotrakul, A Chabry, P Bigey… - Scientific reports, 2021 - nature.com
The Plasmodium falciparum erythrocyte-membrane-protein-1 (PF3D7_1150400/PF11_0521
) contains both domain cassette DC13 and DBLβ3 domain binding to EPCR and ICAM-1 …
) contains both domain cassette DC13 and DBLβ3 domain binding to EPCR and ICAM-1 …
Conus venom fractions inhibit the adhesion of Plasmodium falciparum erythrocyte membrane protein 1 domains to the host vascular receptors
A Padilla, S Dovell, O Chesnokov, M Hoggard… - Journal of …, 2021 - Elsevier
Using high-throughput BioPlex assays, we determined that six fractions from the venom of
Conus nux inhibit the adhesion of various recombinant PfEMP-1 protein domains …
Conus nux inhibit the adhesion of various recombinant PfEMP-1 protein domains …