Multiparameter flow cytometry in the evaluation of myelodysplasia: analytical issues: recommendations from the European Leukemianet/International Myelodysplastic …

A Porwit, MC Béné, C Duetz, S Matarraz… - Cytometry Part B …, 2023 - Wiley Online Library
Multiparameter flow cytometry (MFC) is one of the essential ancillary methods in bone
marrow (BM) investigation of patients with cytopenia and suspected myelodysplastic …

Challenges in translational machine learning

A Couckuyt, R Seurinck, A Emmaneel, K Quintelier… - Human Genetics, 2022 - Springer
Abstract Machine learning (ML) algorithms are increasingly being used to help implement
clinical decision support systems. In this new field, we define as “translational machine …

Clinical application of flow cytometry in patients with unexplained cytopenia and suspected myelodysplastic syndrome: A report of the European LeukemiaNet …

AA van de Loosdrecht, W Kern, A Porwit… - Cytometry Part B …, 2023 - Wiley Online Library
This article discusses the rationale for inclusion of flow cytometry (FCM) in the diagnostic
investigation and evaluation of cytopenias of uncertain origin and suspected …

Myelodysplastic neoplasms dissected into indolent, leukaemic and unfavourable subtypes by computational clustering of haematopoietic stem and progenitor cells

MF van Spronsen, S Van Gassen, C Duetz, TM Westers… - Leukemia, 2024 - nature.com
Myelodysplastic neoplasms (MDS) encompass haematological malignancies, which are
characterised by dysplasia, ineffective haematopoiesis and the risk of progression towards …

[HTML][HTML] Artificial intelligence to empower diagnosis of myelodysplastic syndromes by multiparametric flow cytometry

V Clichet, D Lebon, N Chapuis, J Zhu, V Bardet… - …, 2023 - ncbi.nlm.nih.gov
The diagnosis of myelodysplastic syndromes (MDS) might be challenging and relies on the
convergence of cytological, cytogenetic, and molecular factors. Multiparametric flow …

Deep learning assisted mechanotyping of individual cells through repeated deformations and relaxations in undulating channels

C Combs, DD Seith, MJ Bovyn, SP Gross, X Xie… - …, 2022 - pubs.aip.org
Mechanical properties of cells are important features that are tightly regulated and are
dictated by various pathologies. Deformability cytometry allows for the characterization of the …

Optimization of monocyte gating to quantify monocyte subsets for the diagnosis of chronic myelomonocytic leukemia

R Jurado, M Huguet, B Xicoy… - Cytometry Part B …, 2023 - Wiley Online Library
Background The presence of> 94% classical monocytes (MO1, CD14++/CD16‐) in
peripheral blood (PB) has an excellent performance for the diagnosis of chronic …

Loss of hematopoietic progenitors heterogeneity is an adverse prognostic factor in lower-risk myelodysplastic neoplasms

C Dussiau, T Comont, C Knosp, I Vergnolle, C Bravetti… - Leukemia, 2024 - nature.com
Myelodysplastic neoplasms (MDS) are characterized by clonal evolution starting from the
compartment of hematopoietic stem and progenitors cells (HSPCs), leading in some cases …

Flow Cytometric Assessment of Myelodysplastic Syndromes/Neoplasms

X Chen, U Johansson… - Clinics in Laboratory …, 2023 - labmed.theclinics.com
During the process of hematopoiesis, hematopoietic stem cells (HSCs) undergo hierarchical
differentiation and maturation to develop into mature effector cells through a tightly regulated …

Advances in myelodysplastic syndrome

V Santini - Current opinion in oncology, 2021 - journals.lww.com
Advances in myelodysplastic syndrome : Current Opinion in Oncology Advances in
myelodysplastic syndrome : Current Opinion in Oncology Log in or Register Subscribe to …