COVID-19 has been occasionally linked to histologically confirmed cutaneous vasculitis and
a Kawasaki-like vasculitis, with these entities generally having minimal or no lung …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Disorders characterized by ischemia/reperfusion (I/R), such as myocardial infarction, stroke,
and peripheral vascular disease, continue to be among the most frequent causes of …

A hallmark of type 2 diabetes mellitus (T2DM) is the development of pancreatic β cell failure,
which results in insulinopenia and hyperglycemia. We show that the adipokine adipsin has a …

Since its discovery in the 19th century, the complement system has developed into a
clinically significant entity. The complement system has been implicated in a variety of …

▪ Abstract The complement system not only represents an effective innate immune
mechanism of host defense to eradicate microbial pathogens, but it is also widely involved in …

Research in the field of ischemia-reperfusion injury continues to be plagued by the inability
to translate research findings to clinically useful therapies. This may in part relate to the …

Ischemia-reperfusion injury (IRI) is a common occurrence following myocardial infarction,
transplantation, stroke, and trauma that can lead to multiple organ failure, which remains the …

The complement system is increasingly recognized as important in the pathogenesis of
tissue injury in vivo following immune, ischemic, or infectious insults. Within the complement …

Sepsis is a major clinical problem for which therapeutic interventions have been largely
unsuccessful, in spite of promising strategies that were successful in animals, especially …