Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport
protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation …

Over the past decades, obesity has become a rising health problem as the accessibility to
high calorie, low nutritional value food has increased. Research shows that some bioactive …

Plasma metabolite concentrations reflect the activity of tissue metabolic pathways and their
quantitative determination may be informative about pathogenic conditions. We searched for …

Obesity is an epidemic, complex disease that is characterized by increased glucose, lipids,
and low‐grade inflammation in the circulation, among other factors. It creates the perfect …

Obesity, which is a key risk for the development of hyperglycemia, hypertension,
hyperlipidemia and insulin resistance and is totally referred to as the metabolic disorders …

Hepatic stellate cells (HSCs), also known as perisinusoidal cells, are pericytes found in the
perisinusoidal space of the liver. HSCs are the major cell type involved in liver fibrosis …

Vitamin A must be adequately distributed within the body to maintain the functions of
retinoids in the periphery and chromophore production in the eyes. Blood transport of the …

Currently, two-thirds of American adults are overweight or obese. This high prevalence of
overweight/obesity negatively affects the health of the population, as obese individuals tend …

The pathogenic relevance of sphingolipid metabolism is increasingly being recognised.
Here we elaborate on a new player within the sphingolipid field: the degs1 enzyme, a …

Retinoids are vitamin A (retinol) derivatives and complex regulators of adipogenesis by
activating specific nuclear receptors, including the retinoic acid receptor (RAR) and retinoid …