Cryo-electron microscopy (cryo-EM) has emerged as a powerful structure determination
technique. Its most prolific branch is single particle analysis (SPA), a method being used in a …

Within the materials science community, proteins with cage-like architectures are being
developed as versatile nanoscale platforms for use in protein nanotechnology. Much effort …

Here, we describe the third major release of RELION. CPU-based vector acceleration has
been added in addition to GPU support, which provides flexibility in use of resources and …

This article describes the implementation of real-space refinement in the phenix.
real_space_refine program from the PHENIX suite. The use of a simplified refinement target …

Abstract N 6-methyladenosine (m6A) is the most abundant ribonucleotide modification
among eukaryotic messenger RNAs. The m6A “writer” consists of the catalytic subunit m6A …

Recent advances in the field of electron cryomicroscopy (cryo-EM) have resulted in a rapidly
increasing number of atomic models of biomacromolecules that have been solved using this …

Cryogenic electron microscopy (cryo-EM) maps are now at the point where resolvability of
individual atoms can be achieved. However, resolvability is not necessarily uniform …

Complex I (NADH: ubiquinone oxidoreductase) uses the reducing potential of NADH to drive
protons across the energy-transducing inner membrane and power oxidative …

This paper describes outcomes of the 2019 Cryo-EM Model Challenge. The goals were to
(1) assess the quality of models that can be produced from cryogenic electron microscopy …

Micro-crystal electron diffraction (MicroED) combines the efficiency of electron scattering
with diffraction to allow structure determination from nano-sized crystalline samples in …