Prefrontal cortex development in health and disease: lessons from rodents and humans
M Chini, IL Hanganu-Opatz - Trends in neurosciences, 2021 - cell.com
The role of the prefrontal cortex (PFC) takes center stage among unanswered questions in
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
modern neuroscience. The PFC has a Janus-faced nature: it enables sophisticated cognitive …
The nucleus reuniens of the thalamus sits at the nexus of a hippocampus and medial prefrontal cortex circuit enabling memory and behavior
MJ Dolleman-van der Weel, AL Griffin, HT Ito… - Learning & …, 2019 - learnmem.cshlp.org
The nucleus reuniens of the thalamus (RE) is a key component of an extensive network of
hippocampal and cortical structures and is a fundamental substrate for cognition. A common …
hippocampal and cortical structures and is a fundamental substrate for cognition. A common …
Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility
CB Klune, B Jin, LA DeNardo - Elife, 2021 - elifesciences.org
The medial prefrontal cortex (mPFC) and its abundant connections with other brain regions
play key roles in memory, cognition, decision making, social behaviors, and mood …
play key roles in memory, cognition, decision making, social behaviors, and mood …
How development sculpts hippocampal circuits and function
R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …
in the hippocampus, which develops representations of specific events in the context in …
Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling
M Richter, N Murtaza, R Scharrenberg, SH White… - Molecular …, 2019 - nature.com
Atypical brain connectivity is a major contributor to the pathophysiology of
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …
neurodevelopmental disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 …
Reconciling the different faces of hippocampal theta: The role of theta oscillations in cognitive, emotional and innate behaviors
T Korotkova, A Ponomarenko, CK Monaghan… - Neuroscience & …, 2018 - Elsevier
Abstract The theta oscillation (5–10 Hz) is a prominent behavior-specific brain rhythm. This
review summarizes studies showing the multifaceted role of theta rhythm in cognitive …
review summarizes studies showing the multifaceted role of theta rhythm in cognitive …
Electrical activity controls area-specific expression of neuronal apoptosis in the mouse developing cerebral cortex
O Blanquie, JW Yang, W Kilb, S Sharopov, A Sinning… - Elife, 2017 - elifesciences.org
Programmed cell death widely but heterogeneously affects the developing brain, causing
the loss of up to 50% of neurons in rodents. However, whether this heterogeneity originates …
the loss of up to 50% of neurons in rodents. However, whether this heterogeneity originates …
[HTML][HTML] A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice
Disturbed neuronal activity in neuropsychiatric pathologies emerges during development
and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic …
and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic …
Hippocampal-medial prefrontal cortex network dynamics predict performance during retrieval in a context-guided object memory task
JF Morici, NV Weisstaub… - Proceedings of the …, 2022 - National Acad Sciences
Remembering life episodes is a complex process that requires interaction among multiple
brain areas. It is thought that contextual information provided by the hippocampus (HPC) can …
brain areas. It is thought that contextual information provided by the hippocampus (HPC) can …
Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks
Coordinated activity patterns in the developing brain may contribute to the wiring of neuronal
circuits underlying future behavioural requirements. However, causal evidence for this …
circuits underlying future behavioural requirements. However, causal evidence for this …