Elucidation of the tertiary structure of proteins is an important task for biological and medical
studies. AlphaFold, a modern deep-learning algorithm, enables the prediction of protein …

Potassium (K+) channels play vital roles in various physiological functions, including
regulating K+ flow in cell membranes, impacting nervous system signal transduction …

Understanding binding epitopes involved in protein–protein interactions and accurately
determining their structure are long-standing goals with broad applicability in industry and …

The unbinding pathway of a protein complex can vary significantly depending on
biochemical and mechanical factors. Under mechanical stress, a complex may dissociate …

Protein N-acetylation is one of the most abundant co-and post-translational modifications in
eukaryotes, extending its occurrence to chloroplasts within vascular plants. Recently, a …

The recent breakthrough made in the field of three-dimensional (3D) structure prediction by
artificial intelligence softwares, such as initially AlphaFold2 (AF2) and RosettaFold (RF) and …

Depression severely impairs the health of people all over the world. Cognitive dysfunction
due to depression has resulted in a severe economic burden to family and society induced …

The bone sialoprotein-binding protein (Bbp) is a mechanoactive MSCRAMM protein
expressed on the surface of Staphylococcus aureus that mediates adherence of the …

Over a century ago, physicists started broadly relying on theoretical models to guide new
experiments. Soon thereafter, chemists began doing the same. Now, biological research …

The ability to biodegrade polycyclic aromatic hydrocarbons (PAHs) and the catabolic
enzymes responsible for PAH biotransformation in marine bacteria belonging to the family …