Tailored immunity by skin antigen-presenting cells

C Levin, H Perrin, B Combadiere - Human vaccines & …, 2015 - Taylor & Francis
Skin vaccination aims at targeting epidermal and dermal antigen-presenting cells (APCs),
indeed many subsets of different origin endowed with various functions populate the skin …

Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin

SA Shah, RS Oakes, CM Jewell - Advanced Drug Delivery Reviews, 2024 - Elsevier
Immunotherapies have been transformative in many areas, including cancer treatments,
allergies, and autoimmune diseases. However, significant challenges persist in extending …

Specific roles for dendritic cell subsets during initiation and progression of psoriasis

E Glitzner, A Korosec, PM Brunner… - EMBO molecular …, 2014 - embopress.org
Several subtypes of APC s are found in psoriasis patients, but their involvement in disease
pathogenesis is poorly understood. Here, we investigated the contribution of Langerhans …

[HTML][HTML] Dissolving microneedle delivery of nanoparticle-encapsulated antigen elicits efficient cross-priming and Th1 immune responses by murine Langerhans cells

M Zaric, O Lyubomska, C Poux, ML Hanna… - Journal of Investigative …, 2015 - Elsevier
Dendritic cells (DCs) of the skin have an important role in skin-mediated immunity capable of
promoting potent immune responses. We availed of polymeric dissolving microneedle (MN) …

[HTML][HTML] Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1+ DCs in mouse …

S Carpentier, TPV Manh, R Chelbi, S Henri… - Journal of …, 2016 - Elsevier
Dendritic cells (DC) are mononuclear phagocytes which exhibit a branching (dendritic)
morphology and excel at naïve T cell activation. DC encompass several subsets initially …

Activation of Langerhans cells promotes the inflammation in imiquimod-induced psoriasis-like dermatitis

C Xiao, Z Zhu, S Sun, J Gao, M Fu, Y Liu… - Journal of …, 2017 - Elsevier
Abstract Background Langerhans cells (LCs) are epidermis-resident dendritic cells that
sense and mediate stimuli from skin and outside world, and participate in various skin …

Ionic Liquid-Based Transcutaneous Peptide Antitumor Vaccine: Therapeutic Effect in a Mouse Tumor Model

T Shimizu, T Matsuzaki, S Fukuda, C Yoshioka… - The AAPS Journal, 2023 - Springer
Traditional vaccinations need to be injected with needles, and since some people have a
strong aversion to needles, a needle-free alternative delivery system is important. In this …

[HTML][HTML] CCL8 and the immune control of cytomegalovirus in organ transplant recipients

LF Lisboa, A Egli, J Fairbanks, D O'Shea… - American Journal of …, 2015 - Elsevier
Monitoring of cytomegalovirus cell-mediated immunity is a promising tool for the refinement
of preventative and therapeutic strategies posttransplantation. Typically, the interferon-γ …

CD11c+细胞在炎症性皮肤病中的研究进展

杜林钗, 刘兰英, 王和生, 吴文忠 - 分子影像学杂志, 2018 - j-fzyx.com
CD11c 是主要分布于髓样细胞表面的一种跨膜糖蛋白, 与炎症反应, 免疫应答以及免疫细胞的
活化, 转化和增殖等一些重要的病理过程密切相关. CD11c+ 细胞在各种炎症性皮肤病的真皮层 …

Early events after skin injury: Observations on changes in Langerhans cells and Birbeck granules with role of phosphorylase kinase in the injury pathway

M Heng, M Heng - International Journal of Clinical and Experimental …, 2014 - go.gale.com
Background and Aim: To evaluate the role of Langerhans cells (LCs) in the early events of
the injury pathway, we studied activated and unactivated LCs in sequential biopsies from …