Human autoimmune diseases: a comprehensive update

L Wang, FS Wang, ME Gershwin - Journal of internal medicine, 2015 - Wiley Online Library
There have been significant advances in our understanding of human autoimmunity that
have led to improvements in classification and diagnosis and, most importantly, research …

[HTML][HTML] Gut microbiota in various childhood disorders: Implication and indications

NK Saeed, M Al-Beltagi, AS Bediwy… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Gut microbiota has a significant role in gut development, maturation, and immune system
differentiation. It exerts considerable effects on the child's physical and mental development …

Peripheral nerve injury and myelination: Potential therapeutic strategies

M Modrak, MAH Talukder… - Journal of …, 2020 - Wiley Online Library
Traumatic peripheral nerve injury represents a major clinical and public health problem that
often leads to significant functional impairment and permanent disability. Despite modern …

The emerging epigenetic role of CD8+ T cells in autoimmune diseases: a systematic review

Q Deng, Y Luo, C Chang, H Wu, Y Ding… - Frontiers in …, 2019 - frontiersin.org
Autoimmune diseases are usually complex and multifactorial, characterized by aberrant
production of autoreactive immune cells and/or autoantibodies against healthy cells and …

Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus

Y Ma, X Xu, M Li, J Cai, Q Wei, H Niu - Molecular medicine, 2019 - Springer
Objectives Systemic lupus erythematosus (SLE) is a chronic autoimmune disease whose
onset and progression are affected by genetic and environmental factors. The purpose of …

Rheumatoid arthritis–celiac disease relationship: Joints get that gut feeling

A Lerner, T Matthias - Autoimmunity reviews, 2015 - Elsevier
Rheumatoid arthritis (RA) and celiac disease (CD) belong to the autoimmune disease
family. Despite being separate entities they share multiple aspects. Epidemiologically they …

Microbiota at the crossroads of autoimmunity

O Shamriz, H Mizrahi, M Werbner, Y Shoenfeld… - Autoimmunity …, 2016 - Elsevier
Autoimmune diseases have a multifactorial etiology including genetic and environmental
factors. Recently, there has been increased appreciation of the critical involvement of the …

Whole-genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus …

H Zhu, W Mi, H Luo, T Chen, S Liu, I Raman… - Arthritis research & …, 2016 - Springer
Background Recent achievement in genetics and epigenetics has led to the exploration of
the pathogenesis of systemic lupus erythematosus (SLE). Identification of differentially …

The histone modification code in the pathogenesis of autoimmune diseases

Y Araki, T Mimura - Mediators of Inflammation, 2017 - Wiley Online Library
Autoimmune diseases are chronic inflammatory disorders caused by a loss of self‐
tolerance, which is characterized by the appearance of autoantibodies and/or autoreactive …

Myeloid-derived suppressor cell: A crucial player in autoimmune diseases

D Xu, C Li, Y Xu, M Huang, D Cui, J Xie - Frontiers in immunology, 2022 - frontiersin.org
Myeloid-derived suppressor cells (MDSCs) are identified as a highly heterogeneous group
of immature cells derived from bone marrow and play critical immunosuppressive functions …