Growth factors enable cells to escape irradiation-induced death (apoptosis). One important
family of growth factors share an epidermal growth factor motif, and all bind to ErbB …

Caveolae are vesicular organelles (50—100‐nm in diameter) that are particularly abundant
in cells of the cardiovascular system, including endothelial cells, smooth muscle cells …

EGF receptor (EGFR) overexpression correlates with metastasis in a variety of carcinomas,
but the underlying mechanisms are poorly understood. We demonstrated that EGF disrupted …

Background Atherosclerosis (AS) is the basis of diabetic macrovascular complications. The
plasma low-density lipoprotein (LDL) particles transcytosis across endothelial cells (ECs) …

Abstract Three-dimensional (3D) cell culture techniques are frequently used to model
alterations in tissue architecture critically important for tumor development. Here, we report …

Abstract Caveolin-1 (Cav1) is a multifunctional scaffolding protein with multiple binding
partners that is associated with cell surface caveolae and the regulation of lipid raft domains …

Caveolae exist at cell surfaces as caveolin-coated invaginations that perform transport and
signalling functions influencing cell growth, apoptosis, angiogenesis and transvascular …

Previously it has been reported that caveolin-1 (cav-1) has antiapoptotic activities in prostate
cancer cells and functions downstream of androgenic stimulation. In this study, we …

Caveolin-1 (Cav-1) is the principal structural component of caveolae membrane domains in
non-muscle cells, including mammary epithelia. There is now clear evidence that caveolin-1 …

Caveolae are flask-shaped invaginations at the plasma membrane that constitute a subclass
of detergent-resistant membrane domains enriched in cholesterol and sphingolipids and …