Traumatic brain injury (TBI) is a growing health concern effecting civilians and military
personnel. Research has yielded a better understanding of the pathophysiology of TBI, but …

Free radical formation and oxidative damage have been extensively investigated and
validated as important contributors to the pathophysiology of acute central nervous system …

Mitochondrial dysfunction and oxidative injury, which contribute to worsening of neurological
deficits and poor clinical outcomes, are hallmarks of secondary brain injury after TBI …

Free radical-induced oxidative damage reactions, and membrane lipid peroxidation (LP), in
particular, are among the best validated secondary injury mechanisms in preclinical …

With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

The brain contains a highly diversified complement of molecular species of a mitochondria-
specific phospholipid, cardiolipin, which, because of its polyunsaturation, can readily …

Magnesium deficiency (MgD) has been shown to impact numerous biological processes at
the cellular and molecular levels. In the present review, we discuss the relationship between …

Oxidative stress, an imbalance between oxidants and antioxidants, contributes to the
pathogenesis of traumatic brain injury (TBI). Oxidative neurodegeneration is a key mediator …

Aging is characterized by significant physiological changes, with the degree of decline
varying significantly among individuals. The preservation of intrinsic capacity over the …

Approximately 1.7 million people in the United States annually experience a traumatic brain
injury (TBI). 1 The number of unreported head injuries is much higher. Sports-related head …