NSAID-induced reactions: classification, prevalence, impact, and management strategies
N Blanca-Lopez, V Soriano… - Journal of Asthma …, 2019 - Taylor & Francis
Nonsteroidal anti-inflammatory drugs (NSAIDs) are the leading cause of hypersensitivity
drug reactions. The different chemical structures, cyclooxygenase 1 (COX-1) and/or COX-2 …
drug reactions. The different chemical structures, cyclooxygenase 1 (COX-1) and/or COX-2 …
Efficient prediction of drug–drug interaction using deep learning models
P Kumar Shukla, P Kumar Shukla, P Sharma… - IET Systems …, 2020 - Wiley Online Library
A drug–drug interaction or drug synergy is extensively utilised for cancer treatment.
However, prediction of drug–drug interaction is defined as an ill‐posed problem, because …
However, prediction of drug–drug interaction is defined as an ill‐posed problem, because …
NSAIDs hypersensitivity: questions not resolved
N Blanca-Lopez, ML Somoza-Alvarez… - Current Opinion in …, 2018 - journals.lww.com
The precise evaluation of patients with NSAIDs hypersensitivity following established
guidelines will improve not only our understanding but also the management of these …
guidelines will improve not only our understanding but also the management of these …
Review on databases and bioinformatic approaches on pharmacogenomics of adverse drug reactions
Pharmacogenomics has been used effectively in studying adverse drug reactions by
determining the person-specific genetic factors associated with individual response to a …
determining the person-specific genetic factors associated with individual response to a …
An adaptable in silico ensemble model of the arachidonic acid cascade
M Uttley, G Horne, A Tsigkinopoulou… - Molecular …, 2024 - pubs.rsc.org
Eicosanoids are a family of bioactive lipids, including derivatives of the ubiquitous fatty acid
arachidonic acid (AA). The intimate involvement of eicosanoids in inflammation motivates …
arachidonic acid (AA). The intimate involvement of eicosanoids in inflammation motivates …
Pharmacodynamics simulation of HOEC by a computational model of arachidonic acid metabolic network
W Yang, X Wang, K Li, Y Liu, Y Liu… - Quantitative …, 2019 - Wiley Online Library
Background Arachidonic acid (AA) metabolic network is activated in the most inflammatory
related diseases, and small‐molecular drugs targeting AA network are increasingly …
related diseases, and small‐molecular drugs targeting AA network are increasingly …