[HTML][HTML] Systematic review of viscoelastic testing (TEG/ROTEM) in obstetrics and recommendations from the women's SSC of the ISTH
A Amgalan, T Allen, M Othman, HK Ahmadzia - Journal of Thrombosis and …, 2020 - Elsevier
Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) are point‐of‐care
viscoelastic devices that use whole blood samples to assess coagulation and fibrinolysis …
viscoelastic devices that use whole blood samples to assess coagulation and fibrinolysis …
Tranexamic acid for acute hemorrhage: a narrative review of landmark studies and a critical reappraisal of its use over the last decade
H Lier, M Maegele, A Shander - Anesthesia & Analgesia, 2019 - journals.lww.com
The publication of the Clinical Randomization of an Antifibrinolytic in Significant
Hemorrhage-2 (CRASH-2) study and its intense dissemination prompted a renaissance for …
Hemorrhage-2 (CRASH-2) study and its intense dissemination prompted a renaissance for …
Tranexamic acid dose–response relationship for antifibrinolysis in postpartum haemorrhage during Caesarean delivery: TRACES, a double-blind, placebo-controlled …
AS Ducloy-Bouthors, S Gilliot, M Kyheng… - British Journal of …, 2022 - Elsevier
Background The optimal dose of tranexamic acid to inhibit hyperfibrinolysis in postpartum
haemorrhage is unclear. Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Cesarean …
haemorrhage is unclear. Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Cesarean …
[HTML][HTML] Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery
Essentials• Tranexamic acid (TXA) is an antifibrinolytic drug used to reduce bleeding.•
Assaying plasmin generation (PG) in plasma detects clinically relevant TXA levels in vitro …
Assaying plasmin generation (PG) in plasma detects clinically relevant TXA levels in vitro …
The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries
R Picetti, L Miller, H Shakur-Still, T Pepple… - BMC Pregnancy and …, 2020 - Springer
Background Post-partum haemorrhage (PPH) is a leading cause of maternal death
worldwide. The WOMAN trial assessed the effects of tranexamic acid (TXA) on death and …
worldwide. The WOMAN trial assessed the effects of tranexamic acid (TXA) on death and …
Tranexamic acid and obstetric hemorrhage: give empirically or selectively?
A Shander, M Javidroozi, L Sentilhes - International Journal of Obstetric …, 2021 - Elsevier
Antifibrinolytic agents such as tranexamic acid (TXA) inhibit the fibrinolytic pathway and
protect blood clots from being degraded, thereby promoting hemostasis. They have been …
protect blood clots from being degraded, thereby promoting hemostasis. They have been …
[HTML][HTML] Tranexamic acid for post-partum haemorrhage: What, who and when
Tranexamic acid reduces bleeding by inhibiting the breakdown of blood clots. It is cost-
effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced …
effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced …
Viscoelastic testing: Critical appraisal of new methodologies and current literature
GD Wool, T Carll - International Journal of Laboratory …, 2023 - Wiley Online Library
Abstract United States Food and Drug Administration (FDA)‐approved viscoelastic testing
(VET) methodologies have significantly changed in the last 10 years, with the availability of …
(VET) methodologies have significantly changed in the last 10 years, with the availability of …
The role of tranexamic acid in the management of postpartum haemorrhage
AS Bouthors, S Gilliot, L Sentilhes, B Hennart… - Best Practice & …, 2022 - Elsevier
In the last decades, tranexamic acid (TXA) has emerged as an essential tool in blood loss
management in obstetrics. TXA prophylaxis for postpartum haemorrhage (PPH) has been …
management in obstetrics. TXA prophylaxis for postpartum haemorrhage (PPH) has been …
Tranexamic acid administered during cesarean delivery in high-risk patients: maternal pharmacokinetics, pharmacodynamics, and coagulation status
Background Tranexamic acid is frequently administered for postpartum hemorrhage. The
World Health Organization recommends 1 g intravenous dosing, repeated once after 30 …
World Health Organization recommends 1 g intravenous dosing, repeated once after 30 …