Evidence-based recommendations for local antimicrobial strategies and dead space management in fracture-related infection

WJ Metsemakers, AT Fragomen… - … of orthopaedic trauma, 2020 - journals.lww.com
Fracture-related infection (FRI) remains a challenging complication that imposes a heavy
burden on orthopaedic trauma patients. The surgical management eradicates the local …

Strategies to prevent surgical site infections in acute-care hospitals: 2022 Update

MS Calderwood, DJ Anderson, DW Bratzler… - Infection Control & …, 2023 - cambridge.org
The intent of this document is to highlight practical recommendations in a concise format
designed to assist acute-care hospitals in implementing and prioritizing their surgical-site …

[HTML][HTML] Surgical site infection prophylaxis and wound management in spine surgery

AJ White, B Fiani, R Jarrah, AA Momin… - Asian Spine …, 2022 - ncbi.nlm.nih.gov
Surgical site infection (SSI) is a potentially devastating complication of spinal surgery that
increases patient morbidity and healthcare costs. SSIs have complex and multifactorial …

[HTML][HTML] Intrawound vancomycin in primary hip and knee arthroplasty: a safe and cost-effective means to decrease early periprosthetic joint infection

NN Patel, GN Guild III, AR Kumar - Arthroplasty today, 2018 - Elsevier
Background Periprosthetic joint infection (PJI) is a devastating complication after hip and
knee arthroplasty. Intrawound vancomycin has been described extensively in the spine …

No effect of vancomycin powder to prevent infection in primary total knee arthroplasty: a retrospective review of 976 cases

IA Yavuz, OF Oken, AO Yildirim, F Inci… - Knee Surgery …, 2020 - Wiley Online Library
Purpose Vancomycin powder (VP) has been used to prevent periprosthetic joint infection
(PJI). However, studies investigating the efficacy of VP to prevent infection in primary total …

The effect of prophylactic vancomycin powder on infections following spinal surgeries: a systematic review

V Dodson, N Majmundar, V Swantic, R Assina - Neurosurgical focus, 2019 - thejns.org
OBJECTIVE The use of vancomycin powder in spine surgery for prophylaxis against surgical
site infections (SSIs) is well debated in the literature, with the majority of studies …

Meta-analysis of topical vancomycin powder for microbial profile in spinal surgical site infections

S Li, H Rong, X Zhang, Z Zhang, C Wang, R Tan… - European Spine …, 2019 - Springer
Objectives To systematically evaluate the impact of topical vancomycin powder for microbial
profile in spinal surgical site infections. Methods All available literature regarding the topical …

The impact of prophylactic intraoperative vancomycin powder on microbial profile, antibiotic regimen, length of stay, and reoperation rate in elective spine surgery

ZJ Grabel, A Boden, DN Segal, S Boden, AH Milby… - The Spine Journal, 2019 - Elsevier
Abstract Background Context There is growing concern that the microbial profile of surgical
site infection (SSI) in the setting of prophylactic vancomycin powder may favor more resistant …

Intrawound antibiotic powder in acetabular fracture open reduction internal fixation does not reduce surgical site infections

KH Cichos, CA Spitler, JH Quade… - … of orthopaedic trauma, 2021 - journals.lww.com
Objectives: To compare the risks of surgical site infection (SSI) and postoperative
complications after acetabular fracture open reduction internal fixation (ORIF) in patients …

Microbiome medicine: this changes everything

JC Alverdy - Journal of the American College of Surgeons, 2018 - journals.lww.com
It is becoming increasingly clear that within a given microbial sample, be it from a lake, soil,
or human effluvia, most of the microbes present are uncultivatable and therefore, their …