[HTML][HTML] European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …
[HTML][HTML] The neuroprotective effects of glucagon-like peptide 1 in Alzheimer's and Parkinson's disease: An in-depth review
N Reich, C Hölscher - Frontiers in Neuroscience, 2022 - frontiersin.org
Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …
Protective properties of GLP‐1 and associated peptide hormones in neurodegenerative disorders
C Hölscher - British journal of pharmacology, 2022 - Wiley Online Library
Type 2 diabetes mellitus and the associated desensitisation of insulin signalling has been
identified as a risk factor for progressive neurodegenerative disorders such as Alzheimer's …
identified as a risk factor for progressive neurodegenerative disorders such as Alzheimer's …
Glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1: incretin actions beyond the pancreas
Y Seino, D Yabe - Journal of diabetes investigation, 2013 - Wiley Online Library
Glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1)
are the two primary incretin hormones secreted from the intestine on ingestion of various …
are the two primary incretin hormones secreted from the intestine on ingestion of various …
DPP-4 inhibition by linagliptin attenuates obesity-related inflammation and insulin resistance by regulating M1/M2 macrophage polarization
Dipeptidyl peptidase 4 (DPP-4) cleaves a large number of chemokine and peptide
hormones involved in the regulation of the immune system. Additionally, DPP-4 may also be …
hormones involved in the regulation of the immune system. Additionally, DPP-4 may also be …
Inside the diabetic brain: role of different players involved in cognitive decline
Diabetes mellitus is the most common metabolic disease, and its prevalence is increasing. A
growing body of evidence, both in animal models and epidemiological studies, has …
growing body of evidence, both in animal models and epidemiological studies, has …
Lixisenatide, a drug developed to treat type 2 diabetes, shows neuroprotective effects in a mouse model of Alzheimer's disease
PL McClean, C Hölscher - Neuropharmacology, 2014 - Elsevier
Type 2 diabetes is a risk factor for developing Alzheimer's disease (AD). In the brains of AD
patients, insulin signalling is desensitised. The incretin hormone Glucagon-like peptide-1 …
patients, insulin signalling is desensitised. The incretin hormone Glucagon-like peptide-1 …
Glimepiride ameliorates renal toxicity induced by cadmium in mice: Modulation of Jun N terminal kinase (JNK)/nuclear factor kappa B (NF-κB) and phosphatidylinositol …
Aims Nephrotoxicity is one of the most serious health consequences of cadmium (Cd) toxic
exposure. Cd was associated with nephrotoxicity through different mechanisms including …
exposure. Cd was associated with nephrotoxicity through different mechanisms including …
Diabetes drugs and neurological disorders: new views and therapeutic possibilities
C Patrone, O Eriksson, D Lindholm - The lancet Diabetes & …, 2014 - thelancet.com
Type 2 diabetes is a metabolic disease characterised by insulin resistance with
hyperglycaemia and dyslipidaemia. It is associated with increased risk of stroke and …
hyperglycaemia and dyslipidaemia. It is associated with increased risk of stroke and …
Effects on clinical outcomes of adding dipeptidyl peptidase-4 inhibitors versus sulfonylureas to metformin therapy in patients with type 2 diabetes mellitus
Background: Recent studies concluded that dipeptidyl peptidase-4 (DPP-4) inhibitors
provide glycemic control but also raised concerns about the risk for heart failure in patients …
provide glycemic control but also raised concerns about the risk for heart failure in patients …