Tumour metastasis is the main cause of cancer related deaths. Metastasis is an intricate
multi-step process that requires the acquisition of several cancer cell features, including the …

Background Changes in protein glycosylation are widely observed in tumor cells. N-glycan
branching through adding β1, 6-linked N-acetylglucosamine (β1, 6-GlcNAc) to an α1, 6 …

Protein glycosylation is an important posttranslational process, which regulates protein
folding and functional expression. Studies have shown that abnormal glycosylation in tumor …

High-parameter single-cell phenotyping has enabled in-depth classification and
interrogation of immune cells, but to date has not allowed for glycan characterization. Here …

Metastasis is the main cause of mortality in renal cell carcinoma (RCC). Circular RNAs
(circRNAs) involvement in RCC metastasis has been described, although the underlying …

BACKGROUND: E-cadherin is a cell–cell adhesion molecule and the dysfunction of which is
a common feature of more than 70% of all invasive carcinomas, including gastric cancer …

Papaya (Carica papaya L.) is a fleshy fruit with a rapid pulp softening during ripening.
Ripening events are accompanied by gradual depolymerization of pectic polysaccharides …

Changes in glycosylation, which is one of the most common protein post-translational
modifications, are considered to be a hallmark of cancer. N-glycans can modulate cell …

We present direct evidence that the N-glycosylation state of neural cadherin impacts the
intrinsic kinetics of cadherin-mediated intercellular binding. Micropipette manipulation …

Tunicamycin is an inhibitor of glycosylation that disturbs protein folding machinery in
eukaryotic cells. Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic …